Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
An ultrasensitive sensing strategy based on CRISPR/Cas13a and T7 RNA polymerase amplification for detection of extracellular vesicles. [PDF]
Ran F +6 more
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RNA Polymerase III-Transcribed RNAs in Health and Disease: Mechanisms, Dysfunction, and Future Directions. [PDF]
Sun L, Chen M, Wang X.
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Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation. [PDF]
Zhang L +5 more
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Multi-omics analysis reveals RNA polymerase II degradation as a novel mechanism of PF-3758309's anti-tumor activity. [PDF]
Jia X +11 more
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LIET model: capturing the kinetics of RNA polymerase from loading to termination. [PDF]
Stanley JT +5 more
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Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Sebesta M +10 more
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