Ancient origin, functional conservation and fast evolution of DNA-dependent RNA polymerase III [PDF]
, 2006 RNA polymerase III contains seventeen subunits in yeasts (Saccharomyces cerevisiae and Schizosaccharomyces pombe) and in human cells. Twelve of them are akin to the core RNA polymerase I or II.
Proshkin, Sergey A. +5 more
core +4 more sources
Cytoplasmic RNA Polymerase in Escherichia coli [PDF]
Journal of Bacteriology, 2001 ABSTRACT To obtain an estimate for the concentration of free functional RNA polymerase in the bacterial cytoplasm, the content of RNA polymerase β and β′ subunits in DNA-free minicells from the minicell-producing Escherichia coli strain χ925 was determined.
Patrick P. Dennis +2 more
openaire +3 more sources
Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes [PDF]
, 2016 Saccharomyces cerevisiae sir2Δ or top1Δ mutants exhibit similar phenotypes involving ribosomal DNA, including (i) loss of transcriptional silencing, resulting in non-coding RNA hyperproduction from cryptic RNA polymerase II promoters; (ii) alterations ...
Bjornsti, Mary Ann +6 more
core +1 more source
Taxonomy of Phleboviruses, Emphasizing Those That Are Sandfly-Borne
Viruses, 2021 Sandfly-borne phleboviruses (phylum Negarnavaricota, realm Riboviria, kingdom Orthornavirae, genus Phlebovirus) comprise three genome segments of ribonucleic acid (RNA) and which encode an RNA-dependent RNA polymerase, which they use to transcribe the ...
Charles H. Calisher, Mattia Calzolari
doaj +1 more source
Model of Transcriptional Activation by MarA in Escherichia coli [PDF]
, 2009 We have developed a mathematical model of transcriptional activation by MarA in Escherichia coli, and used the model to analyze measurements of MarA-dependent activity of the marRAB, sodA, and micF promoters in mar-rob- cells. The model rationalizes an unexpected poor correlation between the mid-point of in vivo promoter activity profiles and in vitro ...
arxiv +1 more source
RNA polymerase II from mutant and wild type strains of Caenorhabditis elegans [PDF]
, 1985 Includes vita.Studies of transcription in Caenorhabditis elegans, a model organism for the study of developmental genetics, should contribute to an understanding of the developmental process in metazoans.
Sanford, Thomas Robert
core
Identification of DHX33 as a mediator of rRNA synthesis and cell growth [PDF]
, 2011 In this report, we employed a lentiviral RNA interference screen to discover nucleolar DEAD/DEAH-box helicases involved in RNA polymerase I (Pol I)-mediated transcriptional activity.
Forys, Jason T +4 more
core +3 more sources
Design and use of Chikungunya virus replication templates utilizing mammalian and mosquito RNA polymerase I mediated transcription [PDF]
, 2019 Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. It has a positive sense RNA genome that also serves as the mRNA for four non-structural proteins (nsPs) representing subunits of the viral replicase.
Alphey, Luke +6 more
core +2 more sources
RNA Polymerase from the Fungus Aspergillus nidulans [PDF]
European Journal of Biochemistry, 1979 The DNA‐dependent RNA polymerase I (or A) from the lower eukaryote Aspergillus nidulans has been purified on a large scale to apparent homogeneity by homogenizing the fungal hyphae in liquid nitrogen, extraction of the enzyme at high salt concentration, precipitation of RNA polymerase activity with polymin P (a polyethylene imine), elution of the RNA ...
Stunnenberg, H.G. +2 more
openaire +3 more sources
Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity
Cell Reports, 2020 Summary: Health and survival in old age can be improved by changes in gene expression. RNA polymerase (Pol) I is the essential, conserved enzyme whose task is to generate the pre-ribosomal RNA (rRNA). We find that reducing the levels of Pol I activity is
Guillermo Martínez Corrales +8 more
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