Results 141 to 150 of about 1,401,767 (284)

A Chemical Kinetic Model of Transcriptional Elongation [PDF]

open access: yesarXiv, 2006
A chemical kinetic model of the elongation dynamics of RNA polymerase along a DNA sequence is introduced. The proposed model governs the discrete movement of the RNA polymerase along a DNA template, with no consideration given to elastic effects. The model's novel concept is a ``look-ahead'' feature, in which nucleotides bind reversibly to the DNA ...
arxiv  

The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3

open access: yesEMBO Journal, 2000
RNA polymerase I (Pol I) is dedicated to transcription of the large ribosomal DNA (rDNA). The mechanism of Pol I recruitment onto rDNA promoters is poorly understood.
G. Peyroche   +7 more
semanticscholar   +1 more source

Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1991
The 35S rRNA gene of the yeast Saccharomyces cerevisiae was fused to the GAL7 promoter. This hybrid gene, when present on a multicopy plasmid and induced by galactose, suppressed the growth defects of a temperature-sensitive RNA polymerase I (pol I ...
Y. Nogi, R. Yano, Masayasu Nomura
semanticscholar   +1 more source

Transcriptional Regulation by the Numbers 1: Models [PDF]

open access: yesarXiv, 2004
The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, how fast, when and where. Whether discussing the level of gene expression in a bacterium or its precise location within a developing embryo, the natural language for these ...
arxiv  

Studies on nuclear RNA polymerases and the role of cyclic nucleotides on transcription [PDF]

open access: yes
1. An assay for measuring the endogenous RNA polymerase activity in Tetrahymena pyriformis nuclei was developed. The reaction rate was linear for 60 minutes at 25°C. This rate of the reaction was dependent on the presence of four nucleoside triphosphates
Nadjati, Amira
core  

Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription.

open access: yesGenes & Development, 2008
Actin is associated with all three nuclear RNA polymerases and acts in concert with nuclear myosin I (NM1) to drive transcription. Practically nothing is known regarding the state of actin and the functional interplay of actin and NM1 in transcription ...
Jing Ye   +3 more
semanticscholar   +1 more source

Monoclonal antibody to RNA polymerase I of the silkworm.

open access: yesJournal of Biological Chemistry, 1983
RNA polymerase I has been purified from the silk glands of the silkworm and antibodies obtained from immunized BALB/C mice. Hybridomas were obtained by fusing spleen cells from the same mice with SP-2/0 cells. One of the cloned hybridomas was injected into mice to produce ascitic fluid.
S Sridhara, S Gowda
openaire   +3 more sources

Close temporal relationship between onset of cancer and scleroderma in patients with RNA polymerase I/III antibodies.

open access: yesArthritis & Rheumatism, 2010
OBJECTIVE This study was undertaken to examine the temporal relationship between scleroderma development and malignancy, and to evaluate whether this differs by autoantibody status among affected patients.
Ami A. Shah   +4 more
semanticscholar   +1 more source

RNA polymerase motors on DNA track: effects of traffic congestion on RNA synthesis [PDF]

open access: yesarXiv, 2007
RNA polymerase (RNAP) is an enzyme that synthesizes a messenger RNA (mRNA) strand which is complementary to a single-stranded DNA template. From the perspective of physicists, an RNAP is a molecular motor that utilizes chemical energy input to move along the track formed by a ssDNA.
arxiv  

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