Results 141 to 150 of about 1,401,767 (284)
A Chemical Kinetic Model of Transcriptional Elongation [PDF]
A chemical kinetic model of the elongation dynamics of RNA polymerase along a DNA sequence is introduced. The proposed model governs the discrete movement of the RNA polymerase along a DNA template, with no consideration given to elastic effects. The model's novel concept is a ``look-ahead'' feature, in which nucleotides bind reversibly to the DNA ...
arxiv
RNA polymerase I (Pol I) is dedicated to transcription of the large ribosomal DNA (rDNA). The mechanism of Pol I recruitment onto rDNA promoters is poorly understood.
G. Peyroche+7 more
semanticscholar +1 more source
The 35S rRNA gene of the yeast Saccharomyces cerevisiae was fused to the GAL7 promoter. This hybrid gene, when present on a multicopy plasmid and induced by galactose, suppressed the growth defects of a temperature-sensitive RNA polymerase I (pol I ...
Y. Nogi, R. Yano, Masayasu Nomura
semanticscholar +1 more source
Transcriptional Regulation by the Numbers 1: Models [PDF]
The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, how fast, when and where. Whether discussing the level of gene expression in a bacterium or its precise location within a developing embryo, the natural language for these ...
arxiv
Studies on nuclear RNA polymerases and the role of cyclic nucleotides on transcription [PDF]
1. An assay for measuring the endogenous RNA polymerase activity in Tetrahymena pyriformis nuclei was developed. The reaction rate was linear for 60 minutes at 25°C. This rate of the reaction was dependent on the presence of four nucleoside triphosphates
Nadjati, Amira
core
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription.
Actin is associated with all three nuclear RNA polymerases and acts in concert with nuclear myosin I (NM1) to drive transcription. Practically nothing is known regarding the state of actin and the functional interplay of actin and NM1 in transcription ...
Jing Ye+3 more
semanticscholar +1 more source
Monoclonal antibody to RNA polymerase I of the silkworm.
RNA polymerase I has been purified from the silk glands of the silkworm and antibodies obtained from immunized BALB/C mice. Hybridomas were obtained by fusing spleen cells from the same mice with SP-2/0 cells. One of the cloned hybridomas was injected into mice to produce ascitic fluid.
S Sridhara, S Gowda
openaire +3 more sources
OBJECTIVE This study was undertaken to examine the temporal relationship between scleroderma development and malignancy, and to evaluate whether this differs by autoantibody status among affected patients.
Ami A. Shah+4 more
semanticscholar +1 more source
RNA polymerase motors on DNA track: effects of traffic congestion on RNA synthesis [PDF]
RNA polymerase (RNAP) is an enzyme that synthesizes a messenger RNA (mRNA) strand which is complementary to a single-stranded DNA template. From the perspective of physicists, an RNAP is a molecular motor that utilizes chemical energy input to move along the track formed by a ssDNA.
arxiv
DNA dependent RNA polymerase from vegetative cells and from spores of B.Subtilis: III. Isolation of a stimulating factor [PDF]
Pierre Kerjan, Jekisiel Szulmajster
openalex +1 more source