Results 171 to 180 of about 1,002,934 (332)

U6 snRNA genes ofArabidopsisare transcribed by RNA polymerase III but contain the same two upstream promoter elements as RNA polymerase ll-transcribed U-snRNA genes [PDF]

, 1990
Franz Waibel, Witold Filipowicz
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Escherichia coli RNA-Polymerase Binding Sites on DNA Are Only 14 Base Pairs Long and Are Located between Sequences That Are Very Rich in A+T

, 1974
Paolo U. Giacomoni, J.Y. Le Talaër, Jean Bernard Le Pecq   +2 more
openalex   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Yeast RNA polymerase I binds preferentially to A+T-rich linkers in rDNA

, 1982
Odd S. Gabrielsen, Tordis B. Øyen
openalex   +2 more sources

Highly efficient 5\u27 capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase [PDF]

, 2018
Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and NADH, using NAD+ and NADH as non-canonical initiating nucleotides for transcription
Basu, Urmimala, Bird, Jeremy G, Ebright, Richard H., Grudzien-Nogalska, Ewa, Kiledjian, Megerditch, Kuster, David, Nickels, Bryce E., Patel, Smita S., Ramachandran, Aparna, Temiakov, Dmitry, Towheed, Atif, Wallace, Douglas C.   +11 more
core   +1 more source

The A12.2 Subunit Plays an Integral Role in Pyrophosphate Release of RNA Polymerase I. [PDF]

J Mol Biol, 2023
Fuller KB, Jacobs RQ, Schneider DA, Lucius AL.   +3 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

RNA polymerase I (Pol I) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source