Results 241 to 250 of about 950,582 (330)

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu   +9 more
wiley   +1 more source

DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer. [PDF]

open access: yesNat Commun
Yang ZZ   +21 more
europepmc   +1 more source

RNA polymerase I (Pol I) lobe-binding subunit Rpa12.2 promotes RNA cleavage and proofreading. [PDF]

open access: yesJ Biol Chem, 2022
Schwank K   +5 more
europepmc   +1 more source

On the fidelity of transcription by escherichia coli RNA polymerase [PDF]

open access: bronze, 1980
Olga N. Ozoline   +2 more
openalex   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah   +9 more
wiley   +1 more source

RNA polymerase II ternary transcription complexes generatedin vitro [PDF]

open access: green, 1983
Steven J. Ackerman   +3 more
openalex   +1 more source

Review 1 - Nature (Busby) [PDF]

open access: yes, 2009
Scarlato, Vincenzo
core  

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale   +6 more
wiley   +1 more source

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