Results 81 to 90 of about 1,401,767 (284)
Viruses, 2016 An influenza virus polymerase reconstitution assay based on the human, dog, or chicken RNA polymerase I (PolI) promoter has been developed and widely used to study the polymerase activity of the influenza virus in corresponding cell types. Although it is
Gang Lu +5 more
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Fusarium oxysporum Associated with Fusarium Wilt on Pennisetum sinese in China
Pathogens, 2022 Pennisetum sinese, a versatile and adaptable plant, plays an essential role in phytoremediation, soil reclamation, and fodder production. From 2018 to 2021, the occurrence of Fusarium wilt, with symptoms of foliar blight and internal discoloration of the
Jiaqi Zheng +3 more
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Crystal structure of RNA polymerase I [PDF]
Acta Crystallographica Section A Foundations and Advances, 2014 In eukaryotes ribosome biosynthesis starts with ribosomal RNA production by RNA polymerase I (Pol I), a process that is critical to regulate cell growth and proliferation. We were able to obtain the crystal structure of yeast Pol I, a 14-subunit complex with a total mass of 590 kDa, at 3.0 Å resolution [1].
openaire +2 more sources
Cancer Research, 2011 Deregulated ribosomal RNA synthesis is associated with uncontrolled cancer cell proliferation. RNA polymerase (Pol) I, the multiprotein complex that synthesizes rRNA, is activated widely in cancer.
D. Drygin +17 more
semanticscholar +1 more source
Development of a species-specific RNA polymerase I-based shRNA expression vector [PDF]
, 2006 RNA interference (RNAi) can be induced in vitro either by application of synthetic short interfering RNAs (siRNAs), or by intracellular expression of siRNAs or short hairpin RNAs (shRNAs) from transfected vectors. The most widely used promoters for siRNA/
Graf, Cornelia +7 more
core +2 more sources
Estrogen-induced modification of uterine RNA polymerase activity depends on localization of the estrogen receptor [PDF]
Archives of Biological Sciences, 2007 The aim of this study was to examine the effects of estradiol (E2) on activity of RNA polymerase I and RNA polymerase II in uterine nuclei of ovariectomized (OVX) female rats.
Žakula Zorica +5 more
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Viruses, 2022 Alternaria fungus can cause notable diseases in cereals, ornamental plants, vegetables, and fruits around the world. To date, an increasing number of mycoviruses have been accurately and successfully identified in this fungus.
Wenqing Wang +8 more
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Molecular and Cellular Biology, 2016 RNA polymerase I-mediated rRNA production is a key determinant of cell growth. Despite extensive studies, the signaling pathways that control RNA polymerase I-mediated rRNA production are not well understood.
Chuanyue Wu +4 more
semanticscholar +1 more source
Electrostatic map of T7 DNA. Comparative analysis of functional and electrostatic properties of T7 RNA polymerase specific promoters [PDF]
, 2013 The entire T7 bacteriophage genome contains 39937 base pairs (Database NCBI RefSeq N1001604). Here, electrostatic potential distribution around double helical T7 DNA was calculated by Coulomb method using the computer program of Sorokin A.A. Electrostatic profiles of 17 promoters recognized by T7 phage specific RNA polymerase were analyzed.
arxiv +1 more source
rRNA Promoters as Targets for Transcription Factors: Structural and Functional Studies of PhERI and CarD [PDF]
, 2012 Transcription, the process of copying information encoded in DNA into RNA, to facilitate the expression of encoded proteins, is a central process in all living organisms. The expression and repression of subsets of genes allows different cell types in an
Osmundson, Joseph S
core +1 more source