Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation. [PDF]
Gondane A, Itkonen HM.
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Notch induces transcription by stimulating release of paused RNA polymerase II. [PDF]
Rogers JM +6 more
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Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Sebesta M +10 more
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Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters. [PDF]
Shah SZ +8 more
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DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts. [PDF]
Kuś K +8 more
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SSUP-72/PINN-1 coordinates RNA-polymerase II 3' pausing and developmental gene expression in C. elegans. [PDF]
Stubbe FX +3 more
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RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription
Sadurni MM +8 more
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The RNA Polymerase II Elongation Complex
Annual Review of Biochemistry, 1995▪ Abstract Synthesis of eukaryotic mRNA by RNA polymerase II is an elaborate biochemical process that requires the concerted action of a large set of transcription factors. RNA polymerase II transcription proceeds through multiple stages designated preinitiation, initiation, and elongation.
T, Aso, J W, Conaway, R C, Conaway
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Regulation of RNA polymerase II transcription
Current Opinion in Cell Biology, 1993Transcription initiation plays a central role in the regulation of gene expression. Exciting developments in the last year have furthered our understanding of the interactions between general transcription factors and how these factors respond to modulators of transcription.
R, Drapkin, A, Merino, D, Reinberg
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Eukaryotic RNA polymerase II contains two distinct structural domains: a catalytic core consisting of subunits that are homologous to other multisubunit RNA polymerases, and a unique extension of the carboxy-terminus of the largest subunit comprising tandem repeats of the seven amino acid sequence YSPTSPS. This repetitive 'tail' domain is essential for
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