Results 131 to 140 of about 2,793,309 (370)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Oligonucleotide microarray analysis of aminoallyl-labeled cDNA targets from linear RNA amplification

BioTechniques, 2004
Single-stranded long oligonucleotide-based (50- to 70-mer) microarrays offer several advantages over conventional cDNA microarrays. These include the easy preparation of the probes, low cost of array production, and low cross-contamination during probe ...
Pal Kaposi-Novak, Ju-Seog Lee, Arsen Mikaelyan, Vyomesh Patel, Snorri S. Thorgeirsson   +4 more
doaj   +1 more source

Enzymatic production of single-molecule FISH and RNA capture probes

bioRxiv, 2017
Arrays of singly-labelled short oligonucleotides that hybridize to a specific target revolutionized RNA biology, enabling quantitative, single molecule microscopy analysis and high efficiency RNA/RNP capture.
Imre Gáspár, Frank Wippich, A. Ephrussi   +2 more
semanticscholar   +1 more source

Nanodiagnostic method for colorimetric detection of Mycobacterium tuberculosis 16S rRNA

, 2008
A nanodiagnostic method using nucleic acid sequence-based amplification (NASBA) and gold nanoparticle probes (AuNP probes) was developed for colorimetric detection of Mycobacterium tuberculosis.
Abdul-Tehrani, H., Ghaemi, A., Ghalami, M., Gill, P., Mosavari, N., Sadeghizadeh, M.   +5 more
core   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Mapping m⁶A Sites on HIV-1 RNA Using Oligonucleotide LC-MS/MS

Methods and Protocols
The biological significance of chemical modifications to the ribonucleic acid (RNA) of human immunodeficiency virus type-1 (HIV-1) has been recognized.
Alice Baek, Asif Rayhan, Ga-Eun Lee, Sarah Golconda, Hannah Yu, Shihyoung Kim, Patrick A. Limbach, Balasubrahmanyam Addepalli, Sanggu Kim   +8 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Use of defective interfering particle RNA probes in the determination of the order of in vitro transcription of vesicular stomatitis virus genes [PDF]

, 1977
D. V. R. Reddy, William M. Schnitzlein, M.E. Reichmann   +2 more
openalex   +1 more source

Gene diagnosis of viroids: comparison of return-PAGE and hybridization using DIG-labeled DNA and RNA probes for practical diagnosis of hop stunt, citrus exocortis and apple scar skin viroids in their natural host plants

, 1995
Return-PAGE was reliable for diagnosis of HSVd in hop, CEVd in citron and ASSVd in apple, but was not reliable for HSVd in grapevine and citron, and ASSVd in pear, because of their low concentration.
Shifang Li, S. Onodera, T. Sano, Kouji Yoshida, Guo-Ping Wang, E. Shikata   +5 more
semanticscholar   +1 more source

Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis [PDF]

, 1990
Expression of the Lactate Dehydrogenase (LDH) genes during various stages of spermatogenesis was studied by using a combination of Northern blot analyses and in situ hybridization techniques.
Bellvé, Anthony, Del Mazo, Jesus, Eversole, Pam, Hiraoka, Yukihiro, Li, Steven S. L., Simon, Melvin, Thomas, Kelwyn   +6 more
core