Results 201 to 210 of about 616,337 (352)

Optimization of Structure‐Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS‐CoV‐2 [PDF]

Harald Schwalbe, Betül Ceylan, Jennifer Adam, Sabrina Toews, Frank J. Kaiser, Jonas Doerr, Daniel Scheppa, Jan‐Niklas Tants, Alexandria Smart, Julian Schoth, Stephan Philipp, Elke Stirnal, Jan Ferner, Christian Richter, Sridhar Sreeramulu, Neva Caliskan, Andreas Schlundt, Julia E. Weigand, Michael Göbel, Anna Wacker   +19 more
openalex   +1 more source

Application of environmental sample processor (ESP) methodology for quantifying Pseudo‐nitzschia australis using ribosomal RNA‐targeted probes in sandwich and fluorescent in situ hybridization formats [PDF]

, 2006
Dianne I. Greenfield, Roman Marin, Scott Jensen, Eugene Massion, Brent Roman, Jason Feldman, Christopher A. Scholin   +6 more
openalex   +1 more source

Molecular dynamics simulations with grand-canonical reweighting suggest cooperativity effects in RNA structure probing experiments

, 2022
Nicola Calonaci, Mattia Bernetti, Alisha Jones, Michael Sattler, Giovanni Bussi   +4 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Detailed probing of RNA structure in vivo [PDF]

Nature Reviews Genetics, 2015
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

1P265 Collection and quantification of messenger RNA from tissue models by double barrel carbon probe(21A. Genome biology: Genome analysis,Poster)

, 2013
Yuji Nashimoto, Yasufumi Takahashi, Ryosuke Takano, Kosuke Miyashita, Shukuyo Yamada, Kosuke Ino, Hitoshi Shiku, Tomokazu Matsue   +7 more
openalex   +2 more sources

Activity-based RNA probes [PDF]

Nature Methods, 2014
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Interactions of Protonated Guanidine and Guanidine Derivatives with Multiply Deprotonated RNA Probed by Electrospray Ionization and Collisionally Activated Dissociation [PDF]

, 2017
Jovana Vušurović, Eva‐Maria Schneeberger, Kathrin Breuker   +2 more
openalex   +1 more source