Results 191 to 200 of about 10,995,303 (306)

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

<i>Schizosaccharomyces pombe</i> Telomerase RNA: Secondary Structure and Flexible-Scaffold Function. [PDF]

Mol Cell Biol
McMurdie K, Peeney AN, Mefford MA, Baumann P, Zappulla DC.   +4 more
europepmc   +1 more source

e-RNA: a collection of web-servers for the prediction and visualisation of RNA secondary structure and their functional features. [PDF]

Nucleic Acids Res, 2023
Tsybulskyi V, Semenchenko E, Meyer IM.
europepmc   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

TVAE-RNA: ensemble-based RNA secondary structure prediction via transformer variational autoencoders. [PDF]

Bioinformatics
Mei X, Liu H, Zhu Y, Zhao E, Li L, Zhang H.   +5 more
europepmc   +1 more source

REDfold: accurate RNA secondary structure prediction using residual encoder-decoder network. [PDF]

BMC Bioinformatics, 2023
Chen CC, Chan YM.
europepmc   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Unfolding of RNA secondary structure impairs RNA stability to fine-tune phosphate starvation responses in rice roots. [PDF]

Plant Commun
Jin Q, Gao R, Yao J, Huang Z, Liu K, Wei G, Dong W, Wang Z.   +7 more
europepmc   +1 more source

RNAsmc: A integrated tool for comparing RNA secondary structure and evaluating allosteric effects. [PDF]

Comput Struct Biotechnol J, 2023
Wang H, Lu X, Zheng H, Wang W, Zhang G, Wang S, Lin P, Zhuang Y, Chen C, Chen Q, Qu J, Xu L.   +11 more
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source