Results 201 to 210 of about 526,558 (303)

R2DT: a comprehensive platform for visualizing RNA secondary structure. [PDF]

Nucleic Acids Res
McCann H, Meade CD, Williams LD, Petrov AS, Johnson PZ, Simon AE, Hoksza D, Nawrocki EP, Chan PP, Lowe TM, Ribas CE, Sweeney BA, Madeira F, Anyango S, Appasamy SD, Deshpande M, Varadi M, Velankar S, Zirbel CL, Naiden A, Jossinet F, Petrov AI.   +21 more
europepmc   +1 more source

Sequence similarity governs generalizability of de novo deep learning models for RNA secondary structure prediction. [PDF]

PLoS Comput Biol, 2023
Qiu X.
europepmc   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Short tandem repeat variants are possibly associated with RNA secondary structure and gene expression. [PDF]

PLoS One
Kinney N, Pathak D, Evans E, Arias P.
europepmc   +1 more source

bpRNA-align: improved RNA secondary structure global alignment for comparing and clustering RNA structures. [PDF]

RNA, 2023
Lasher B, Hendrix DA.
europepmc   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Enhanced Generalizability of RNA Secondary Structure Prediction via Convolutional Block Attention Network and Ensemble Learning. [PDF]

Molecules
Lin H, Hou D, Li Z, Wang S, Liu Y, Gu J, Qian J, Yin R, Zhao H, Wang S, Chen Y, Ju D, Zeng X.   +12 more
europepmc   +1 more source

Deciphering phenotyping, DNA barcoding, and RNA secondary structure predictions in eggplant wild relatives provide insights for their future breeding strategies. [PDF]

Sci Rep, 2023
Mohanty S, Mishra BK, Dasgupta M, Acharya GC, Singh S, Naresh P, Bhue S, Dixit A, Sarkar A, Sahoo MR.   +9 more
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Comprehensive benchmarking of large language models for RNA secondary structure prediction. [PDF]

Brief Bioinform
Zablocki LI, Bugnon LA, Gerard M, Di Persia L, Stegmayer G, Milone DH.   +5 more
europepmc   +1 more source