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Combinatorics of Saturated Secondary Structures of RNA
Journal of Computational Biology, 2006Following Zuker (1986), a saturated secondary structure for a given RNA sequence is a secondary structure such that no base pair can be added without violating the definition of secondary structure, e.g., without introducing a pseudoknot. In the Nussinov-Jacobson energy model (Nussinov and Jacobson, 1980), where the energy of a secondary structure is ...
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Secondary structure in transfer RNA genes
Journal of Molecular Biology, 1973The bacterial strand of the heteroduplex of λh80 dglyTsu+36tyrTthrT with λh80 carries a cluster of three transfer RNA genes. The bacterial strands of the heteroduplexes of φ80hpsu+,−III and φ80hpsu−III with φ80h carry two and one genes for tyrosine tRNA, respectively.
M, Wu, N, Davidson
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Analysis of RNA Secondary Structure
2014RNA has different levels of structural organization. The primary structure is the linear order of the nucleotide monomers, the RNA sequence. During transcription process, the partially synthesized RNA is folded by base-pairing and thermodynamic intramolecular or intermolecular interactions.
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Combinatorial Properties of RNA Secondary Structures
Journal of Computational Biology, 2002The secondary structure of an RNA molecule is of great importance and possesses influence, e.g., on the interaction of tRNA molecules with proteins or on the stabilization of mRNA molecules. The classification of secondary structures by means of their order proved useful with respect to numerous applications.
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DNA-RNA hybrid secondary structures
Journal of Molecular Biology, 1986DNA-RNA and DNA-DNA duplexes are even more polymorphic than observed previously. DNA-RNA hybrids can have secondary structures like A-DNA or A-RNA, but double helices of the synthetic DNA-RNA hybrids poly(dA) X poly(rU) and poly(dI) X poly(rC), respectively, form 11-fold and 10-fold double-helical structures in which the two chains have quite different
S, Arnott +3 more
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2006
The three-dimensional structures of nucleic acids, RNA, and DNA, are dominated by double-helical regions that are formed by canonical Watson–Crick and wobble (GU) base pairs, which collectively are referred to as the secondary structure of the molecule.
Ivo L. Hofacker +2 more
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The three-dimensional structures of nucleic acids, RNA, and DNA, are dominated by double-helical regions that are formed by canonical Watson–Crick and wobble (GU) base pairs, which collectively are referred to as the secondary structure of the molecule.
Ivo L. Hofacker +2 more
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Evolutionary Conservation of RNA Secondary Structure
2023Noncoding RNAs, ncRNAs, naturally fold into structures, which allow them to perform their functions in the cell. Evolutionarily close species share structures and functions. This occurs because of shared selective pressures, resulting in conserved groups.
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Introduction to RNA Secondary Structure Comparison
2013Many methods have been proposed for RNA secondary structure comparison, and new ones are still being developed. In this chapter, we first consider structure representations and discuss their suitability for structure comparison. Then, we take a look at the more commonly used methods, restricting ourselves to structures without pseudo-knots.
Schirmer, Stefanie +2 more
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The fractal nature of RNA secondary structure
Naturwissenschaften, 1989The secondary structure of RNA is vital to the function of this molecule in biological systems. Studying the organization of these complex structures may prove useful in understanding the origin and evolution of these intricate assemblies, and their relation to RNA's functional ...
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RNA Secondary Structure Determination by NMR
2016Dynamic programming methods for predicting RNA secondary structure often use thermodynamics and experimental restraints and/or constraints to limit folding space. Chemical mapping results typically restrain certain nucleotides not to be in AU or GC pairs.
Jonathan L, Chen +2 more
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