Results 251 to 260 of about 10,995,303 (306)

Determination of IL-6 Gene Promoter Polymorphism in Patients with Hepatitis C and Its Impact on RNA Secondary Structure. [PDF]

Medicina (Kaunas)
Sadiq S, Anwar MZ, Shafique H, Manzoor SM, Shoaib S, Hamid R, Hashmi SN, Ashraf NM, Afsar T, Bhat MA, Razak S.   +10 more
europepmc   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

RNAformer: A Simple yet Effective Model for Homology-Aware RNA Secondary Structure Prediction

Franke JK, Runge F, Köksal R, Matus D, Backofen R, Hutter F.   +5 more
europepmc   +1 more source

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Metrics on RNA Secondary Structures

Journal of Computational Biology, 2000
Many different programs have been developed for the prediction of the secondary structure of an RNA sequence. Some of these programs generate an ensemble of structures, all of which have free energy close to that of the optimal structure, making it important to be able to quantify how similar these different structures are.
Vincent Moulton, Michael Zuker, Mike A. Steel, Robin Pointon, David Penny   +4 more
openaire   +3 more sources

Secondary structure of Qβ RNA

Journal of Theoretical Biology, 1977
Abstract The complete set of possible secondary structures of a variant Qβ RNA sequenced by Schaffner has been found using a computer program which allows G-U pairing as well as the usual Watson-Crick A-U and G-C pairing. Of special interest are those secondary structures with the highest double-strandedness.
I R, Lapidus, B, Rosen, R, Hepperle
openaire   +2 more sources

Secondary Structure of Ribosomal RNA

Science, 1970
Infrared spectra were obtained for 16 S and for 23 S ribosomal RNA's in D 2 O solutions. The percentage of each base in the paired and unpaired regions of the RNA was determined from the spectra. The secondary structures of 16 S and 23
K A, Hartman, G J, Thomas
openaire   +2 more sources

Similarity of RNA secondary structures

Journal of Computational Chemistry, 2006
AbstractIn this article, we propose a relatively similar measure to compare RNA secondary structures. We first transform an RNA secondary structure into a special sequence representation. Then, on the basis of symbolic sequence complexity, we obtain the relative distance of RNA secondary structures.
Chun Li, Ai-hua Wang, Lili Xing
openaire   +3 more sources

5S RNA secondary structure

Nature, 1975
NUMEROUS attempts have been made to deduce a secondary structure of 5S RNA1–4. Differing approaches have yielded various structures, but each turns out to be inconsistent with either physical, chemical, biochemical, or comparative evidence. Clearly the situation is not analogous to that which obtained for transfer RNA (tRNA).
G E, Fox, C R, Woese
openaire   +2 more sources