Results 271 to 280 of about 526,558 (303)

Combinatorial Properties of RNA Secondary Structures

Journal of Computational Biology, 2002
The secondary structure of an RNA molecule is of great importance and possesses influence, e.g., on the interaction of tRNA molecules with proteins or on the stabilization of mRNA molecules. The classification of secondary structures by means of their order proved useful with respect to numerous applications.
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DNA-RNA hybrid secondary structures

Journal of Molecular Biology, 1986
DNA-RNA and DNA-DNA duplexes are even more polymorphic than observed previously. DNA-RNA hybrids can have secondary structures like A-DNA or A-RNA, but double helices of the synthetic DNA-RNA hybrids poly(dA) X poly(rU) and poly(dI) X poly(rC), respectively, form 11-fold and 10-fold double-helical structures in which the two chains have quite different
S, Arnott, R, Chandrasekaran, R P, Millane, H S, Park   +3 more
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RNA Secondary Structures

2006
The three-dimensional structures of nucleic acids, RNA, and DNA, are dominated by double-helical regions that are formed by canonical Watson–Crick and wobble (GU) base pairs, which collectively are referred to as the secondary structure of the molecule.
Ivo L. Hofacker, Peter F. Stadler, Peter F. Stadler   +2 more
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Evolutionary Conservation of RNA Secondary Structure

2023
Noncoding RNAs, ncRNAs, naturally fold into structures, which allow them to perform their functions in the cell. Evolutionarily close species share structures and functions. This occurs because of shared selective pressures, resulting in conserved groups.
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Introduction to RNA Secondary Structure Comparison

2013
Many methods have been proposed for RNA secondary structure comparison, and new ones are still being developed. In this chapter, we first consider structure representations and discuss their suitability for structure comparison. Then, we take a look at the more commonly used methods, restricting ourselves to structures without pseudo-knots.
Schirmer, Stefanie, Ponty, Yann, Giegerich, Robert   +2 more
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The fractal nature of RNA secondary structure

Naturwissenschaften, 1989
The secondary structure of RNA is vital to the function of this molecule in biological systems. Studying the organization of these complex structures may prove useful in understanding the origin and evolution of these intricate assemblies, and their relation to RNA's functional ...
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RNA Secondary Structure Determination by NMR

2016
Dynamic programming methods for predicting RNA secondary structure often use thermodynamics and experimental restraints and/or constraints to limit folding space. Chemical mapping results typically restrain certain nucleotides not to be in AU or GC pairs.
Jonathan L, Chen, Stanislav, Bellaousov, Douglas H, Turner   +2 more
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Implications of secondary structure in messenger RNA

Journal of Theoretical Biology, 1972
Abstract The physical properties and nucleotide sequences of some messenger RNA molecules suggest the presence of extensive base-paired secondary structure. This paper evaluates the evolutionary conflict between this secondary structure and the encoded amino acid sequence, and concludes that selection pressure for specific base-pairing in a messenger
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UFold: fast and accurate RNA secondary structure prediction with deep learning

Nucleic Acids Research, 2022
Laiyi Fu, Jie Wu, Qinke Peng
exaly  

Computational Prediction of RNA Secondary Structure

2013
The purpose of this section is to detail methods for the computational prediction of RNA secondary structure. This protocol is intended to provide an easy entry into the field of RNA structure prediction for those wishing to utilize it in their research and to suggest 'best practices' for going from sequence to secondary structure depending on the ...
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