Results 271 to 280 of about 10,995,303 (306)

Analysis of RNA Secondary Structure

2014
RNA has different levels of structural organization. The primary structure is the linear order of the nucleotide monomers, the RNA sequence. During transcription process, the partially synthesized RNA is folded by base-pairing and thermodynamic intramolecular or intermolecular interactions.
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RNA Secondary Structures

2006
The three-dimensional structures of nucleic acids, RNA, and DNA, are dominated by double-helical regions that are formed by canonical Watson–Crick and wobble (GU) base pairs, which collectively are referred to as the secondary structure of the molecule.
Ivo L. Hofacker, Peter F. Stadler, Peter F. Stadler   +2 more
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Evolutionary Conservation of RNA Secondary Structure

2023
Noncoding RNAs, ncRNAs, naturally fold into structures, which allow them to perform their functions in the cell. Evolutionarily close species share structures and functions. This occurs because of shared selective pressures, resulting in conserved groups.
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Secondary structure of ovalbumin messenger RNA

Biochemistry, 1976
The secondary structure of highly purified ovalbumin mRNA was studied by automated thermal denaturation techniques and the data were subjected to computer processing. Comparative studies with 20 natural and synthetic model nucleic acids suggested that the secondary structure of ovalbumin mRNA possesses the following features: the extent of base pairing
N T, Van, J W, Holder, S L, Woo, A R, Means, B W, O'Malley   +4 more
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Introduction to RNA Secondary Structure Comparison

2013
Many methods have been proposed for RNA secondary structure comparison, and new ones are still being developed. In this chapter, we first consider structure representations and discuss their suitability for structure comparison. Then, we take a look at the more commonly used methods, restricting ourselves to structures without pseudo-knots.
Schirmer, Stefanie, Ponty, Yann, Giegerich, Robert   +2 more
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The evolution of 5S RNA secondary structures

Canadian Journal of Biochemistry, 1978
We have applied the Pipas–McMahon algorithm based on free energy calculations to the search for a 5S RNA base-pair structure common to all known sequences. We find that a 'Y'-shaped model is consistently among the structures having the lowest free energy using 5S RNA sequences from either eukaryotic or prokaryotic sources.
D, Sankofff, A M, Morin, R J, Cederhren
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The fractal nature of RNA secondary structure

Naturwissenschaften, 1989
The secondary structure of RNA is vital to the function of this molecule in biological systems. Studying the organization of these complex structures may prove useful in understanding the origin and evolution of these intricate assemblies, and their relation to RNA's functional ...
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RNA Secondary Structure Determination by NMR

2016
Dynamic programming methods for predicting RNA secondary structure often use thermodynamics and experimental restraints and/or constraints to limit folding space. Chemical mapping results typically restrain certain nucleotides not to be in AU or GC pairs.
Jonathan L, Chen, Stanislav, Bellaousov, Douglas H, Turner   +2 more
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Implications of secondary structure in messenger RNA

Journal of Theoretical Biology, 1972
Abstract The physical properties and nucleotide sequences of some messenger RNA molecules suggest the presence of extensive base-paired secondary structure. This paper evaluates the evolutionary conflict between this secondary structure and the encoded amino acid sequence, and concludes that selection pressure for specific base-pairing in a messenger
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Modulation of Noncoding RNAs (ncRNAs) and Their Potential Role as Therapeutics

Medical Epigenetics, 2021
Luciano Pirola, Aneta Balcerczyk, Oskar Ciesielski   +2 more
exaly