Results 131 to 140 of about 1,674,122 (352)

Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer. [PDF]

Cells, 2023
Shiino S, Tokura M, Nakayama J, Yoshida M, Suto A, Yamamoto Y.   +5 more
europepmc   +1 more source

A computer aided oligonucleotide analysis provides a model sequence for RNA polymerase-promoter recognition in E.coli [PDF]

, 1978
Günther E.F. Scherer, Malcolm D. Walkinshaw, Struther Arnott   +2 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses [PDF]

, 1978
Yueh‐hsiu Chien, Inder M. Verma, Thomas Y. Shih, Edward M. Scolnick, Norman Davidson   +4 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Identification of Rat Testicular Leydig Precursor Cells by Single-Cell-RNA-Sequence Analysis. [PDF]

Front Cell Dev Biol, 2022
Guan X, Chen P, Ji M, Wen X, Chen D, Zhao X, Huang F, Wang J, Shao J, Xie J, Zhao X, Chen F, Tian J, Lin H, Zirkin BR, Duan P, Su Z, Chen H.   +17 more
europepmc   +1 more source

Nucleotide Sequence Analysis of RNA Synthesized from Rabbit Globin Complementary DNA [PDF]

, 1974
Raymond Poon, Gary V. Paddock, Howard C. Heindell, Philip Whitcome, Winston Salser, D. L. Kacian, Arthur Bank, Roberto Gambino, Francesco Ramirez   +8 more
openalex   +1 more source

Influence of viral genes on the cell-to-cell spread of RNA silencing [PDF]

The turnip crinkle virus-based vector TCV–GFPDCP had been devised previously to study cell-to-cell and long-distance spread of virus-induced RNA silencing.
Hong, Yiguo, Ryabov, Eugene V., Zhang, Xuemei, Zhou, Yu   +3 more
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

RNA sequence analysis identified bone morphogenetic protein-2 (BMP2) as a biomarker underlying form deprivation myopia. [PDF]

Biochem Biophys Rep, 2022
Chen CW, Yao JY.
europepmc   +1 more source