Results 131 to 140 of about 1,743,892 (345)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

Nature Communications, 2017
Adenosine deaminase acting on RNA 1 (ADAR1) edits adenosine to inosine. Here the authors, using parallel analysis of RNA secondary structure sequencing, provide evidence that ADAR1 induces sequence-context-dependent RNA secondary structures changes ...
Oz Solomon, Ayelet Di Segni, Karen Cesarkas, Hagit T. Porath, Victoria Marcu-Malina, Orel Mizrahi, Noam Stern-Ginossar, Nitzan Kol, Sarit Farage-Barhom, Efrat Glick-Saar, Yaniv Lerenthal, Erez Y. Levanon, Ninette Amariglio, Ron Unger, Itamar Goldstein, Eran Eyal, Gidi Rechavi   +16 more
doaj   +1 more source

Artificial intelligence-based non-small cell lung cancer transcriptome RNA-sequence analysis technology selection guide. [PDF]

Front Bioeng Biotechnol, 2023
Joo MS, Pyo KH, Chung JM, Cho BC.
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A multi-objective fuzzy model based on enhanced artificial fish Swarm for multiple RNA sequences alignment

Egyptian Informatics Journal
Ribonucleic Acid (RNA) sequence alignment is a fundamental operation in bioinformatics, essential for analyzing the physicochemical and functional characteristics of RNA molecules.
Medhat A. Tawfeek, Ibrahim Alrashdi, Madallah Alruwaili, Gamal Farouk Elhady   +3 more
doaj   +1 more source

RNA sequence analysis of nasopharyngeal swabs from asymptomatic and mildly symptomatic patients with COVID-19. [PDF]

Int J Infect Dis, 2022
Faridl M, Mellyani K, Khoirunnisa K, Septiani P, Giri-Rachman EA, Nugrahapraja H, Rahmawati E, Alamanda CNC, Ristandi RB, Rachman RW, Robiani R, Fibriani A.   +11 more
europepmc   +1 more source

Locating chemical modifications in RNA sequences through ribonucleases and LC-MS based analysis

, 2021
Priti Thakur, Scott Abernathy, Patrick A. Limbach, Balasubrahmanyam Addepalli   +3 more
openalex   +2 more sources

RNA sequencing analysis of the developing chicken retina

Scientific Data, 2016
AbstractRNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression.
Langouet-Astrie, Christophe J., Meinsen, Annamarie L., Grunwald, Emily R., Turner, Stephen D., Enke, Raymond A.   +4 more
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Oncolytic Virus Affects the RAS Pathway in Cancer: RNA Sequence Analysis. [PDF]

J Oncol Res Ther, 2021
Samouha A, Fogel EJ, Goel S, Maitra R.
europepmc   +1 more source