Results 221 to 230 of about 1,674,122 (352)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae. [PDF]

PLoS One, 2017
Badaoui B, Fougeroux A, Petit F, Anselmo A, Gorni C, Cucurachi M, Cersini A, Granato A, Cardeti G, Formato G, Mutinelli F, Giuffra E, Williams JL, Botti S.   +13 more
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Introductory Editorial: Current Developments in RNA Sequence Analysis

Bioinformatics and Biology Insights, 2016
Jianping Zhang, Shaolei Teng, Cuncong Zhong, Bo Wang, Jie Wu   +4 more
doaj  

RNA-Sequence Analysis Reveals Differentially Expressed Genes (DEGs) in Patients Exhibiting Different Risks of Tumor Metastasis. [PDF]

Med Sci Monit, 2017
Dong LF, Xu SY, Long JP, Wan F, Chen YD.
europepmc   +1 more source

Identification of Mycobacterial Species by Comparative Sequence Analysis of the RNA Polymerase Gene ( rpoB )

, 1999
Bum‐Joon Kim, Seung Hyun Lee, Mi-Ae Lyu, Seo-Jeong Kim, Gill‐Han Bai, Sang‐Jae Kim, Gue‐Tae Chae, Eui-Chong Kim, Chang-Yong Cha, Yoon‐Hoh Kook   +9 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

RNA sequence analysis of rat acute experimental pancreatitis with and without fatty liver: a gene expression profiling comparative study. [PDF]

Sci Rep, 2017
Wang Q, Yan H, Wang G, Qiu Z, Bai B, Wang S, Yu P, Feng Q, Zhao Q, He X, Liu C.   +10 more
europepmc   +1 more source

A thermodynamic analysis of the sequence-specific binding of RNA by bacteriophage MS2 coat protein

, 1998
Hans Johansson, Dagmar Dertinger, Karen A. LeCuyer, Linda S. Behlen, Charles Greef, Olke C. Uhlenbeck   +5 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source