Results 211 to 220 of about 1,335,933 (257)

RNA SEQUENCE ANALYSIS

Annual Review of Biochemistry, 1970
FRACTIONATION AND PURIFICATION OF RNA 228 Transfer RNA 228 Ribosomal RNA ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 230 Viral RNA 230 SEPARATION AND ISOLATION OF POLYNUCLEOTIDES 231 Physical methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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RNA sequencing: the teenage years

Nature Reviews Genetics, 2019
Over the past decade, RNA sequencing (RNA-seq) has become an indispensable tool for transcriptome-wide analysis of differential gene expression and differential splicing of mRNAs. However, as next-generation sequencing technologies have developed, so too has RNA-seq. Now, RNA-seq methods are available for studying many different aspects of RNA biology,
James Hadfield, Rory Stark, Marta Grzelak   +2 more
exaly   +3 more sources

Sequence-specific targeting of RNA

Methods, 2022
Post-transcriptional modifications play an important role in several processes, including translation, splicing, and RNA degradation in eukaryotic cells. To investigate the function of specific modifications it is of high interest to develop tools for sequence-specific RNA-targeting.
Lukas, Rösner, Dennis, Reichert, Kristina, Rau, Nils, Muthmann, Andrea, Rentmeister   +4 more
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RNA sequencing

Anesthesiology, 2021
Eliana, Lucchinetti, Michael, Zaugg
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Nanopore RNA Sequencing Analysis

2021
The recent advent of Nanopore sequencing allows for the sequencing of full-length RNA or cDNA molecules. This new type of data introduces new challenges from the computational point of view, and requires new software as well as dedicated analysis pipelines.
Tommaso, Leonardi, Adrien, Leger
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Identification of Circular RNAs using RNA Sequencing

Journal of Visualized Experiments, 2019
Circular RNAs (circRNAs) are a class of non-coding RNAs involved in functions including micro-RNA (miRNA) regulation, mediation of protein-protein interactions, and regulation of parental gene transcription. In classical next generation RNA sequencing (RNA-seq), circRNAs are typically overlooked as a result of poly-A selection during construction of ...
Shobana, Sekar, Philipp, Geiger, Lori, Cuyugan, Annalee, Boyle, Geidy, Serrano, Thomas G, Beach, Winnie S, Liang   +6 more
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Sequence Design for RNA-RNA Interactions

The design of RNA sequences with desired structural properties presents a challenging computational problem with promising applications in biotechnology and biomedicine. Most regulatory RNAs function by forming RNA-RNA interactions, e.g., in order to regulate mRNA expression.
Maria Waldl, Hua-Ting Yao, Ivo L. Hofacker   +2 more
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RNA Sequencing

RNA-sequencing of wild-type and vimentin knockout THP-1 ...
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Identification of Bacterial Small RNAs by RNA Sequencing

2014
Small regulatory RNAs (sRNAs) in bacteria are known to modulate gene expression and control a variety of processes including metabolic reactions, stress responses, and pathogenesis in response to environmental signals. A method to identify bacterial sRNAs on a genome-wide scale based on RNA sequencing (RNA-seq) is described that involves the ...
María, Gómez-Lozano, Rasmus Lykke, Marvig, Søren, Molin, Katherine S, Long   +3 more
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RNA sequencing

1990
Abstract The first complete nucleotide sequence of a gene was published in 1964 by Robert Holley and associates. (1). This sequence was inferred from the transcript of the gene encoding yeast alanine tRNA. Determination of the 77 nucleotide sequence required 1 g of alanine tRNA, recovered from. 200 g of bulk tRNA, isolated from 140 kg
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