Results 1 to 10 of about 1,673,511 (373)
Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
The EMBO Journal, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
core +9 more sources
The Biochemist, 2004 There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be self-regulated by feedback mechanisms.
D. Baulcombe
semanticscholar +4 more sources
RNA decay is an antiviral defense in plants that is counteracted by viral RNA silencing suppressors. [PDF]
PLoS Pathogens, 2018 Exonuclease-mediated RNA decay in plants is known to be involved primarily in endogenous RNA degradation, and several RNA decay components have been suggested to attenuate RNA silencing possibly through competing for RNA substrates.
Fangfang Li, Aiming Wang
doaj +2 more sources
DICER-LIKE2 plays a primary role in transitive silencing of transgenes in Arabidopsis. [PDF]
PLoS ONE, 2008 Dicer-like (DCL) enzymes play a pivotal role in RNA silencing in plants, processing the long double-stranded RNA (dsRNA) that triggers silencing into the primary short interfering RNAs (siRNAs) that mediate it.
Sizolwenkosi Mlotshwa +8 more
doaj +15 more sources
RNA-guided RNA silencing by an Asgard archaeal Argonaute. [PDF]
Nat Commun, 2023 AbstractArgonaute proteins are the central effectors of RNA-guided RNA silencing pathways in eukaryotes, playing crucial roles in gene repression and defense against viruses and transposons. Eukaryotic Argonautes are subdivided into two clades: AGOs generally facilitate miRNA- or siRNA-mediated silencing, while PIWIs generally facilitate piRNA-mediated
Bastiaanssen C +13 more
europepmc +4 more sources
RNA Silencing in the Management of Dyslipidemias. [PDF]
Curr Atheroscler Rep, 2021 Abstract Purpose of Review Remarkable reductions in cardiovascular morbidity and mortality have been achieved in recent decades through the widespread use of ‘small-molecule’ hypolipidaemic drugs such as statins and ezetimibe. An alternative approach is to perturb the production of proteins through ribonucleic acid (RNA)
Henney NC, Banach M, Penson PE.
europepmc +5 more sources
Noncoding RNAs and gene silencing [PDF]
Cell, 2007 Noncoding RNA has long been proposed to control gene expression via sequence-specific interactions with regulatory regions. Here, we review the role of noncoding RNA in heterochromatic silencing and in the silencing of transposable elements (TEs ...
Irvine, D. V. +2 more
core +5 more sources
Identification of RNA silencing suppressor encoded by citrus chlorotic dwarf-associated virus [PDF]
Frontiers in MicrobiologyIntroductionCitrus chlorotic dwarf-associated virus (CCDaV) is an economically important citrus virus associated with leaf curling, deformation, and chlorosis found in China.
Xiao Ye +6 more
doaj +2 more sources
Resistance gene Ty-1 restricts TYLCV infection in tomato by increasing RNA silencing [PDF]
Virology JournalA major antiviral mechanism in plants is mediated by RNA silencing through the action of DICER-like (DCL) proteins, which cleave dsRNA into discrete small RNA fragments, and ARGONAUTE (AGO) proteins, which use the small RNAs to target single-stranded RNA.
Xiaofang Ma +3 more
doaj +2 more sources
RNA silencing movement in plants. [PDF]
Journal of Integrative Plant Biology, 2016 Multicellular organisms, like higher plants, need to coordinate their growth and development and to cope with environmental cues. To achieve this, various signal molecules are transported between neighboring cells and distant organs to control the fate ...
G. Mermigka +2 more
semanticscholar +4 more sources