Results 221 to 230 of about 1,673,511 (373)

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Two mutually exclusive evolutionary scenarios for allexiviruses that overcome host RNA silencing and autophagy by regulating viral CRP expression. [PDF]

PLoS Pathog, 2023
Kim H, Kawakubo S, Takahashi H, Masuta C.   +3 more
europepmc   +1 more source

Epigenetic Reprogramming and Small RNA Silencing of Transposable Elements in Pollen

Cell, 2009
R. Slotkin, M. Vaughn, F. Borges, M. Tanurdžić, J. Becker, J. Feijó, J. Feijó, R. Martienssen   +7 more
semanticscholar   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

RNA silencing of GM-CSF in CAR-T cells reduces the secretion of multiple inflammatory cytokines. [PDF]

Invest New Drugs, 2023
Shang S, Chen Y, Yang X, Yang Y, Wang W, Wang Y.   +5 more
europepmc   +1 more source

Silencing of a viral RNA silencing suppressor in transgenic plants

, 2002
Eugene I. Savenkov, Jari P. T. Valkonen
openalex   +1 more source

Silencing of TonEBP/NFAT5 Transcriptional Activator by RNA Interference [PDF]

, 2003
Ki Young Na, Seung Kyoon Woo, Sang Do Lee, H. Moo Kwon   +3 more
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Nucleoporins shape germ granule architecture and balance small RNA silencing pathways. [PDF]

Nat Commun
Shi K, Zhang Y, Du Z, Liu SC, Leon I, Fan X, Lee HC, Zhang D.   +7 more
europepmc   +1 more source

Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing. [PDF]

Life Sci Alliance, 2023
Alagia A, Tereňová J, Ketley RF, Di Fazio A, Chelysheva I, Gullerova M.   +5 more
europepmc   +1 more source