Results 231 to 240 of about 1,733,662 (377)

Role of SLC16A10 in Psoriasis Through the Regulation of Arachidonic Acid Metabolism in Keratinocytes

open access: yesAdvanced Science, EarlyView.
This study demonstrates that SLC16A10 plays a crucial role in psoriasis pathogenesis through arachidonic acid metabolism regulation in keratinocytes. Using multi‐omics analysis and experimental validation, researchers identify SLC16A10 as both a diagnostic biomarker and therapeutic target.
Jingyuan Yang   +17 more
wiley   +1 more source

RNA silencing of GM-CSF in CAR-T cells reduces the secretion of multiple inflammatory cytokines. [PDF]

open access: yesInvest New Drugs, 2023
Shang S   +5 more
europepmc   +1 more source

Highly activated RNA silencing via strong induction of dicer by one virus can interfere with the replication of an unrelated virus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
S. Chiba, N. Suzuki
semanticscholar   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao   +10 more
wiley   +1 more source

Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing. [PDF]

open access: yesLife Sci Alliance, 2023
Alagia A   +5 more
europepmc   +1 more source

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