Results 241 to 250 of about 1,673,511 (373)
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu+10 more
wiley +1 more source
Proteolytic control of the RNA silencing machinery. [PDF]
Genschik P, Schiaffini M, Lechner E.
europepmc +1 more source
Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection. [PDF]
Liu L+8 more
europepmc +1 more source
G. H. Samuel+4 more
semanticscholar +1 more source
Genetics‐Based Targeting Strategies for Precise Neuromodulation
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He+11 more
wiley +1 more source
Tomato chlorosis virus CPm protein is a pathogenicity determinant and suppresses host local RNA silencing induced by single-stranded RNA. [PDF]
Yang X+10 more
europepmc +1 more source
Dissection of a Natural RNA Silencing Process in the Drosophila melanogaster Germ Line [PDF]
Alexei A. Aravin+5 more
openalex +1 more source
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Role of Bean Yellow Mosaic Virus P1 and HC-Pro in Enhancing Gene Expression and Suppressing RNA Silencing in <i>Nicotiana benthamiana</i>. [PDF]
Choi S+8 more
europepmc +1 more source