Results 251 to 260 of about 1,673,511 (373)

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

open access: yesAdvanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang   +16 more
wiley   +1 more source

A beneficial fungal root endophyte triggers systemic RNA silencing and DNA methylation of a host reporter gene. [PDF]

open access: yesRNA Biol, 2023
Dalakouras A   +8 more
europepmc   +1 more source

The RNA-Induced Silencing Complex Is a Mg2+-Dependent Endonuclease [PDF]

open access: bronze, 2004
Dianne S. Schwarz   +2 more
openalex   +1 more source

RNA silencing sorted [PDF]

open access: yesNature Reviews Molecular Cell Biology, 2010
openaire   +1 more source

Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α

open access: yesAdvanced Science, EarlyView.
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao   +13 more
wiley   +1 more source

Genome-wide identification, characterization and expression analysis of key gene families in RNA silencing in centipedegrass. [PDF]

open access: yesBMC Genomics
Liu S   +10 more
europepmc   +1 more source

Development of an assay system for the analysis of host RISC activity in the presence of a potyvirus RNA silencing suppressor, HC-Pro. [PDF]

open access: yesVirol J, 2023
Hong SF   +10 more
europepmc   +1 more source

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