Results 191 to 200 of about 208,055 (239)
Effect of the OPHN1 novel variant c.1025+1 G>A on RNA splicing: insights from a minigene assay. [PDF]
BMC Med GenomicsYang F, Wang M.
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Genetic variation of circHIBADH enhances prostate cancer risk through regulating HNRNPA1-related RNA splicing. [PDF]
J Biomed ResCheng Y +7 more
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AEP promotes aberrant RNA splicing through DDX3X cleavage in solid tumors. [PDF]
J Clin InvestXie Y, Zhang H, Song X.
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NMR studies of two spliced leader RNAs using isotope labeling
, 1994 Jon Lapham, Donald M. Crothers
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Three exonic variants in the COL4A5 gene alter RNA splicing in a minigene assay. [PDF]
Mol Genet Genomic MedZhang R +8 more
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RNA Splicing by the Spliceosome
Annual Review of Biochemistry, 2020The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades of biochemistry and genetics combined with recent structural studies of the spliceosome have produced a detailed view of the mechanism of splicing. In this review, we aim to make this mechanism understandable and provide several videos of the spliceosome in action to ...
Wilkinson, Max E. +2 more
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Trends in Cancer, 2020
RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers.
Iannis Aifantis, Eric Wang
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RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers.
Iannis Aifantis, Eric Wang
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2018
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Ulrich Laufs +4 more
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Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Ulrich Laufs +4 more
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RNA Splicing in the Chloroplast
2006The chloroplast genomes of Chlamydomonas spp. contain introns that belong to the two major classes found in organelles: group I and group II. Some of the members of both classes are ribozymes capable of self-splicing in vitro and, indeed, most of the group I introns studied in Chlamydomonas spp. are autocatalyic.
Herrin, David L. +2 more
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JAMA: The Journal of the American Medical Association, 1988
The splicing of long transcripts of RNA (copied from DNA in the cell nucleus) into smaller, specific mRNA (ready for export to the protein-producing machinery in the cytoplasm) is an important event in the regulation of gene expression in eukaryotic cells. The splicing reaction occurs as a late step in the nuclear pathway for synthesis of mRNAs.
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The splicing of long transcripts of RNA (copied from DNA in the cell nucleus) into smaller, specific mRNA (ready for export to the protein-producing machinery in the cytoplasm) is an important event in the regulation of gene expression in eukaryotic cells. The splicing reaction occurs as a late step in the nuclear pathway for synthesis of mRNAs.
openaire +3 more sources