Results 221 to 230 of about 375,320 (335)

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

open access: yesAdvanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li   +12 more
wiley   +1 more source

Visualizing RNA splicing [PDF]

open access: yesNature Reviews Molecular Cell Biology, 2013
openaire   +2 more sources

Integrative Omics Reveal Female‐Specific Benefits of p16+ Cell Clearance in Aging Mice

open access: yesAdvanced Science, EarlyView.
Aging causes accumulation of p16⁺ senescent cells that promote inflammation and dysfunction. Multi‐omics analyses reveal striking sex differences in senescent cell burden and clearance: females accumulate more p16⁺ cells, especially in the liver, and their removal rejuvenates molecular and functional profiles.
Yao Lin   +4 more
wiley   +1 more source

Targeting RNA splicing modulation: new perspectives for anticancer strategy? [PDF]

open access: yesJ Exp Clin Cancer Res
Lv X   +8 more
europepmc   +1 more source

Transcription of a nematode trans-spliced leader RNA requires internal elements for both initiation and 3′ end-formation.

open access: bronze, 1990
Gregory J. Hannon   +4 more
openalex   +1 more source

Interpretation of RNA Universe and Coding Potential Using IntRNA

open access: yesAdvanced Science, EarlyView.
This study constructs a multi‐channel deep learning framework IntRNA to interpret RNA universe and coding potential. IntRNA consistently performed the best among existing methods in various benchmarks. Moreover, IntRNA’s interpretability is also validated by real‐world analysis, which found some features indicating long‐distance contact between ...
Yunxia Wang   +8 more
wiley   +1 more source

Oncoprotein TLS Interacts with Serine-Arginine Proteins Involved in RNA Splicing [PDF]

open access: hybrid, 1998
Liu Yang   +3 more
openalex   +1 more source

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