Results 261 to 270 of about 211,496 (309)
Non-coding cause of congenital heart defects: Abnormal RNA splicing with multiple isoforms as a mechanism for heterotaxy. [PDF]
HGG AdvWells JR +6 more
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Yeast Small Ubiquitin-Like Modifier (SUMO) Protease Ulp2 is Involved in RNA Splicing. [PDF]
Dev ReprodPark JM +6 more
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NMR studies of two spliced leader RNAs using isotope labeling
, 1994 Jon Lapham, Donald M. Crothers
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RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer. [PDF]
Mol Ther Nucleic AcidsXie X, Macknight HP, Lu AL, Chalfant CE.
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RNA Splicing by the Spliceosome
Annual Review of Biochemistry, 2020The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades of biochemistry and genetics combined with recent structural studies of the spliceosome have produced a detailed view of the mechanism of splicing. In this review, we aim to make this mechanism understandable and provide several videos of the spliceosome in action to ...
Wilkinson, Max E. +2 more
openaire +3 more sources
Trends in Cancer, 2020
RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers.
Iannis Aifantis, Eric Wang
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RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. Considering the importance of RNA splicing in gene regulation, alterations in this pathway have been implicated in many human cancers.
Iannis Aifantis, Eric Wang
openaire +2 more sources
1992
RNA trans-splicing joins two or more RNA molecules into one RNA molecule. This process is a variation of the more familiar and common intron removal during nuclear pre-mRNA splicing. Both splicing reactions are a series of cleavage and ligation reactions resulting in the precise excision of introns and in the joining of exons to generate mature RNA. In
David Hirsh, Xin-Yun Huang
openaire +3 more sources
RNA trans-splicing joins two or more RNA molecules into one RNA molecule. This process is a variation of the more familiar and common intron removal during nuclear pre-mRNA splicing. Both splicing reactions are a series of cleavage and ligation reactions resulting in the precise excision of introns and in the joining of exons to generate mature RNA. In
David Hirsh, Xin-Yun Huang
openaire +3 more sources
2018
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Ulrich Laufs +4 more
openaire +3 more sources
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules derived from exons by alternative mRNA splicing. Circularization of single-stranded RNA molecules was already described in 1976 for viroids in plants. Since then several additional types of circular RNAs in many species have been described such as the circular single-stranded ...
Ulrich Laufs +4 more
openaire +3 more sources