Results 211 to 220 of about 4,719,315 (357)

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Pet127p, a Membrane-Associated Protein Involved in Stability and Processing of Saccharomyces cerevisiae Mitochondrial RNAs [PDF]

, 1997
Gerlinde Wiesenberger, Thomas D. Fox
openalex   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Nucleotide sequence and stability of the RNA component of RNase P from a temperature-sensitive mutant ofE. coli

, 1983
Hiroshi Sakamoto, Naohiro Kimura, Fumikiyo Nagawa, Yoshiro Shimura   +3 more
openalex   +2 more sources

Effects of site-specific substitution of 5-fluorouridine on the stabilities of duplex DNA and RNA [PDF]

, 1995
Parag V. Sahasrabudhe, Richard T. Pon, William H. Gmeiner   +2 more
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability. [PDF]

Front Mol Neurosci
Reisbitzer A, Hollitzer C, Geraci A, Schaefer J, Burghaus M, Bruns J, Urban J, Kurz T, Krauß S.   +8 more
europepmc   +1 more source

Complete suboptimal folding of RNA and the stability of secondary structures [PDF]

, 1999
Stefan Wuchty, Walter Fontana, Ivo L. Hofacker, Peter Schuster   +3 more
openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Molecular and Environmental Modulators of Aging: Interplay Between Inflammation, Epigenetics, and RNA Stability. [PDF]

Genes (Basel)
Dragoumani K, Kletsas D, Chrousos GP, Vlachakis D, Balatsos NAA.   +4 more
europepmc   +1 more source