Results 241 to 250 of about 15,140,513 (376)

Associating cancer-related RNA structure disrupting SNPs in LincRNAs to function. [PDF]

BMC Genomics
Han X, Anthon C, Geissler AS, Sabarinathan R, Seemann SE, Havgaard JH, Gorodkin J.   +6 more
europepmc   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Conservative Motion Theory – Bio V Fredholm-Stable RNA Folding and Predictive Sequence–Structure Map

Kawasaki, Hideyo
openalex   +1 more source

RNA G-quadruplex structure-based PROTACs for targeted DHX36 protein degradation and gene activity modulation in mammalian cells [PDF]

Kun Zhang, Qichang Nie, Maolin Li, Xiaona Chen, Liting Zhong, Ting Dai, Xiaofan Guo, Haizhou Zhao, Terrence Chi‐Kong Lau, Huating Wang, Shuo‐Bin Chen, Chun Kit Kwok   +11 more
openalex   +1 more source

The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase [PDF]

, 1991
Sophie Roy, Michael B. Agy, Ara G. Hovanessian, Nahum Sonenberg, Michael G. Katze   +4 more
openalex   +1 more source

RNA structure modulates Cas13 activity and enables mismatch detection. [PDF]

Nat Biotechnol
Larsen BB, Kimchi O, Dunkley ORS, Grimm MS, Siegers JY, Huang Y, Vandavasi VG, Nguyen LT, Lamb CH, Aranovich I, Eggink D, Meijer A, Jalal H, Notterman DA, Karlsson EA, Te Velthuis AJW, Myhrvold C.   +16 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

TiRNA: a coarse-grained method with temperature and ion effects for RNA structure folding and prediction. [PDF]

Nucleic Acids Res
Wang X, Zhou Z, Yu S, Tan YL, Shi YZ, Tan ZJ.   +5 more
europepmc   +1 more source

A Hitchhiker's guide to RNA-RNA structure and interaction prediction tools. [PDF]

Brief Bioinform, 2023
Tieng FYF, Abdullah-Zawawi MR, Md Shahri NAA, Mohamed-Hussein ZA, Lee LH, Mutalib NA.   +5 more
europepmc   +1 more source