Results 261 to 270 of about 1,038,708 (317)

Advancing mRNA subcellular localization prediction with graph neural network and RNA structure. [PDF]

Bioinformatics
Li F, Bi Y, Guo X, Tan X, Wang C, Pan S.
europepmc   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

RNA structure: implications in viral infections and neurodegenerative diseases. [PDF]

Adv Biotechnol (Singap)
Lu S, Tang Y, Yin S, Sun L.
europepmc   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Machine learning in RNA structure prediction: Advances and challenges. [PDF]

Biophys J
Zhang S, Li J, Chen SJ.
europepmc   +1 more source

An intra-family conserved high-order RNA structure within the M ORF is important for arterivirus subgenomic RNA accumulation and infectious virus production. [PDF]

J Virol
Shang P, Li Y, Napthine S, Chen C, Brierley I, Firth AE, Fang Y.   +6 more
europepmc   +1 more source

Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling. [PDF]

Nat Commun
Fontana J, Sparkman-Yager D, Faulkner I, Cardiff R, Kiattisewee C, Walls A, Primo TG, Kinnunen PC, Garcia Martin H, Zalatan JG, Carothers JM.   +10 more
europepmc   +1 more source

Probing RNA structure and dynamics using nanopore and next generation sequencing. [PDF]

J Biol Chem
Bose E, Xiong S, Jones AN.
europepmc   +1 more source

The myriad roles of RNA structure in the flavivirus life cycle. [PDF]

RNA Biol
Abram QH, Landry BN, Wang AB, Kothe RF, Hauch HCH, Sagan SM.   +5 more
europepmc   +1 more source

Alternative substrate kinetics of SARS-CoV-2 Nsp15 endonuclease reveals a specificity landscape dominated by RNA structure. [PDF]

Nucleic Acids Res
Kalia N, Snell KC, Harris ME.
europepmc   +1 more source