Results 121 to 130 of about 9,562,225 (293)
Theoretical Search for RNA Folding Nuclei
Entropy, 2015 The functions of RNA molecules are defined by their spatial structure, whose folding is regulated by numerous factors making RNA very similar to proteins.
Leonid B. Pereyaslavets +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Study of RNA Secondary Structure Prediction Algorithms
, 2011 RNA secondary structure study is one of the most important fields in computational molecular biology. According to different conditions, RNA secondary structure prediction derives two ways.
Ying Sun, Sheng Hua Ye, Hong Wei Lu
core +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
RNA secondary structure prediction using homologous sequences (Problem 13).
, 2013 RNA secondary structure prediction using homologous sequences (Problem 13).
Michiaki Hamada (355897) +3 more
core +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
RNA secondary structure prediction by conducting multi-class classifications
Computational and Structural Biotechnology JournalGenerating valid predictions of RNA secondary structures is challenging. Several deep learning methods have been developed for predicting RNA secondary structures.
Jiyuan Yang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Prediction and design of DNA and RNA structures
New Biotechnology, 2010 Computational tools for prediction and design of DNA and RNA structures are used for different approaches in nucleic acid research. The prediction tools are used for the identification and modeling of biologically important nucleic acid structures, whereas the design tools aim at constructing novel molecular architectures and devices for nanotechnology
openaire +2 more sources
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source