Results 201 to 210 of about 9,541,112 (326)

RNA tertiary structure determination: NOE pathways construction by tabu search

Bioinform., 2005
J. Błażewicz, M. Szachniuk, A. Wójtowicz   +2 more
semanticscholar   +1 more source

Thermophilic Adaptation of a Minimal Hammerhead Ribozyme Comes with a Functional Penalty. [PDF]

Biochemistry
Zegher AH, Hanif SF, Kielbasinski EM, Patterson CR, Baker C, Hall RP, Leamy KA.   +6 more
europepmc   +1 more source

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease‐Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan‐Cytology Validation

Advanced Science, EarlyView.
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong, Fan Jiang, Ye Xie, Xiaowei Huang, Runnan Shen, Yun Wang, Mengyi Zhu, Haoxuan Wang, Hongkun Yang, Yanxiao Nie, Zhen Lin, Rui Chen, Nengtai Ouyang, Tianxin Lin, Shaoxu Wu   +14 more
wiley   +1 more source

Probing the Secondary and Tertiary Structure of SARS-CoV-2 Genomic RNA

This thesis covers my graduate research in the DeRose Laboratory, focusing on viral RNA structure probing and the improvement of the determination of RNA tertiary structure conformation.
Willis, Dillon
core   +1 more source

Studies of transfer RNA tertiary structure of singlet-singlet energy transfer.

Proceedings of the National Academy of Sciences of the United States of America, 1974
Chih-Hsin Yang, D. Söll
semanticscholar   +1 more source

mRNA Structure Regulates Translation at Every Step. [PDF]

Biochemistry
Khitun A, Weeks KM.
europepmc   +1 more source

Developing Explicit Base Stacking Potentials for the IsRNA2+ Coarse-Grained RNA Force Field Using Iterative Reweighting. [PDF]

J Chem Theory Comput
Li W, Chen SJ.
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Interdependent RNA structural motifs at the 3'-terminus of the West Nile virus genome regulate viral growth. [PDF]

Nucleic Acids Res
Tsao LH, Brackney DE, Pyle AM.
europepmc   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source