Results 31 to 40 of about 9,541,112 (326)
Analysis and classification of RNA tertiary structures [PDF]
RNA, 2008 There is a fast growing interest in noncoding RNA transcripts. These transcripts are not translated into proteins, but play essential roles in many cellular and pathological processes. Recent efforts toward comprehension of their function has led to a substantial increase in both the number and the size of solved RNA structures.
Mira, Abraham +3 more
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BMC Bioinformatics, 2023 Background CRISPR-Cas-Docker is a web server for in silico docking experiments with CRISPR RNAs (crRNAs) and Cas proteins. This web server aims at providing experimentalists with the optimal crRNA-Cas pair predicted computationally when prokaryotic ...
Ho-min Park +7 more
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SS/SW BASE PAIRS ARE THE ONLY BASE PAIRS INVOLVED IN LONG-RANGE RNA TERTIARY MOTIFS
Journal of Bioinformatics and Genomics, 2020 The structure of noncoding RNAs largely determines their functions. With the rapid growth of experimental data on the RNA secondary structures, the task of predicting its spatial structure becomes the most urgent task of RNA bioinformatics.
Manakov, A.K. +2 more
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RNA Biology, 2022 The internal ribosome entry site (IRES) RNA of bovine viral diarrhoea virus (BVDV), an economically significant Pestivirus, is required for the cap-independent translation of viral genomic RNA. Thus, it is essential for viral replication and pathogenesis.
Devadatta Gosavi +6 more
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The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. [PDF]
PLoS ONE, 2010 Most large ribozymes require protein cofactors in order to function efficiently. The yeast mitochondrial bI3 group I intron requires two proteins for efficient splicing, Mrs1 and the bI3 maturase. Mrs1 has evolved from DNA junction resolvases to function
Caia D S Duncan, Kevin M Weeks
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Nature Communications, 2023 RNAs are fundamental in living cells and perform critical functions determined by their tertiary architectures. However, accurate modeling of 3D RNA structure remains a challenging problem.
Yang Li +5 more
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Regulation of the structure of RNA assemblies through RNA tertiary interactions [PDF]
Nucleic Acids Symposium Series, 2005 We have previously shown that RNA building blocks containing two or three stem-loops based on the dimerization initiation site (DIS) connected by short linkers can be assembled into various one- and two-dimensional structures. Here, in an attempt to regulate the conformation of the RNA assemblies by adjusting the rigidity of the RNA building block, we ...
Rei, Ohmori +2 more
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L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy [PDF]
, 2006 Ribosomal proteins are assumed to stabilize specific RNA structures and promote compact folding of the large rRNA. The conformational dynamics of the protein between the bound and unbound state play an important role in the binding process.
Wöhnert, Jens +9 more
core +2 more sources
A Novel Structural Measure Separating Non-Coding RNAs from Genomic Backgrounds
Tsinghua Science and Technology, 2015 RNA secondary structure has become the most exploitable feature for ab initio detection of non-coding RNA (ncRNA) genes from genome sequences. Previous work has used Minimum Free Energy (MFE) based methods developed to identify ncRNAs by measuring ...
Yingfeng Wang +2 more
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VfoldCPX Server: Predicting RNA-RNA Complex Structure and Stability. [PDF]
PLoS ONE, 2016 RNA-RNA interactions are essential for genomic RNA dimerization, mRNA splicing, and many RNA-related gene expression and regulation processes. The prediction of the structure and folding stability of RNA-RNA complexes is a problem of significant ...
Xiaojun Xu, Shi-Jie Chen
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