Results 231 to 240 of about 3,365,264 (261)

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Integrated RNA-seq and small RNA-seq profiling reveals tissue-associated transcriptional programs and candidate miRNA-mRNA relationships across tea floral tissues. [PDF]

Front Plant Sci
Xing F, Sun F, Xie Q, Li T, Yang J, Heng S, Xu L, Zhang W, Mao G.   +8 more
europepmc   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

Advanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti, Eva Clemente, Emanuela Mensà, Marco de Maria, Fulvia Farabegoli, Emanuela Saracino, Barbara Bortolani, Emanuela Marcelli, Renato Brandimarti, Dario de Biase, Giampaolo Zuccheri   +10 more
wiley   +1 more source

Exogenous 24-epibrassinolide enhances chilling tolerance in <i>Phalaenopsis-type Dendrobium</i> through coordinated physiological and transcriptomic responses. [PDF]

Front Plant Sci
Yu X, Wei X, Yao T, Luo X, Yi S, Liao Y, Li C, Lu S.   +7 more
europepmc   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

RBM15 affects mitophagy in intracerebral hemorrhage by promoting E2F1 nuclear translocation via NXF1. [PDF]

Front Immunol
Sun J, Yin H, Song J, Li N, Feng J, Lu X, Han Y, Zhang Y.   +7 more
europepmc   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Targeting NDUFS4 Disrupts Oxidative Phosphorylation and Induces Ferroptosis in Olaparib-Resistant Prostate Cancer. [PDF]

Mol Cancer Ther
Schaaf ZA, Ning S, Leslie AR, Sharifi M, Gao RY, Maine JP, Leslie KD, Shen Y, Lombard AP, Lou W, Li PK, Liu C, Dall'Era M, Gao AC.   +13 more
europepmc   +1 more source

EgKT2-1, an inwardly rectifying Shaker-type potassium channel in oil palm that correlates with oil yield. [PDF]

Plant Cell Rep
Monder H, Espeout S, Zimmermann SD, Billotte N, Verdeil JL, Bocs S, Ollivier J, Impens R, Jacob F, Gaillard I, Cuéllar T.   +10 more
europepmc   +1 more source

Evaluating the utility of storage solutions to preserve nucleic acid integrity at ambient temperature in South Africa. [PDF]

Afr J Lab Med
Moshoma T, Gededzha MP, Mampeule N, Mayne E.   +3 more
europepmc   +1 more source