Results 101 to 110 of about 1,176,989 (262)

The potential for reassortment between Oropouche and Schmallenberg Orthobunyaviruses [PDF]

open access: yes, 2017
A number of viruses within the Peribunyaviridae family are naturally occurring reassortants, a common phenomenon for segmented viruses. Using a minigenome-reporter and virus-like particle (VLP) production assay, we have accessed the potential of ...
Elliott, Richard M.   +3 more
core   +1 more source

RNA-protein interaction prediction without high-throughput data: An overview and benchmark of in silico tools

open access: yesComputational and Structural Biotechnology Journal
RNA-protein interactions (RPIs) are crucial for accurately operating various processes in and between organisms across kingdoms of life. Mutual detection of RPI partner molecules depends on distinct sequential, structural, or thermodynamic features ...
Sarah Krautwurst, Kevin Lamkiewicz
doaj   +1 more source

Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase [PDF]

open access: hybrid, 2020
Lorillee Tallorin   +8 more
openalex   +1 more source

Genome-scale CRISPR-Cas9 screen identifies host factors as potential therapeutic targets for SARS-CoV-2 infection

open access: yesiScience
Summary: Although many host factors important for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported, the mechanisms by which the virus interacts with host cells remain elusive.
Madoka Sakai   +11 more
doaj   +1 more source

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]

open access: yes, 1985
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A.   +3 more
core  

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

open access: yesNature Communications
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing >80% of ...
Delphine Planas   +24 more
doaj   +1 more source

Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells

open access: yesnpj Viruses
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans.
Takehiro Kanda   +5 more
doaj   +1 more source

In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. [PDF]

open access: yes, 2015
Viruses in the Reoviridae, like the triple-shelled human rotavirus and the single-shelled insect cytoplasmic polyhedrosis virus (CPV), all package a genome of segmented double-stranded RNAs (dsRNAs) inside the viral capsid and carry out endogenous ...
Chang, Winston   +5 more
core  

Determination of the Cell Permissiveness Spectrum, Mode of RNA Replication, and RNA-Protein Interaction of Zika Virus [PDF]

open access: gold, 2017
Wangheng Hou   +6 more
openalex   +1 more source

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