Results 51 to 60 of about 3,436,004 (333)
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
, 2017 Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +2 more sources
Translation of Plant RNA Viruses [PDF]
Viruses, 2021 Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation.
Guowei Geng +7 more
openaire +3 more sources
In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. [PDF]
, 2016 Packaging of the genome into a protein capsid and its subsequent delivery into a host cell are two fundamental processes in the life cycle of a virus. Unlike double-stranded DNA viruses, which pump their genome into a preformed capsid, single-stranded ...
Dai, Xinghong +6 more
core +1 more source
Uirusu, 2005 Actively replicating RNA viruses in nature are continually changing their genetic information by spontaneous mutations. These changes often result in alterations in immune-sensitivity, drug-sensitivity, cell-tropism, and host-range, causing uncontrollability of the pathogen and emerging/re-emerging infections. To better understand the virus changes and
Hironori, Sato, Masaru, Yokoyama
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The diversity and ecology of RNA viruses is severely understudied in complex environments. Here we investigate the diversity and community patterns of soil RNA viruses by analyzing assembled metatranscriptomes.
Evan P. Starr +4 more
semanticscholar +1 more source
Biased Mutation and Selection in RNA Viruses
Molecular biology and evolution, 2020 RNA viruses are responsible for some of the worst pandemics known to mankind, including outbreaks of Influenza, Ebola, and COVID-19. One major challenge in tackling RNA viruses is the fact they are extremely genetically diverse.
T. Kustin, A. Stern
semanticscholar +1 more source
Programmable Inhibition and Detection of RNA Viruses Using Cas13.
Molecules and Cells, 2019 The CRISPR effector Cas13 could be an effective antiviral for single-stranded RNA (ssRNA) viruses because it programmably cleaves RNAs complementary to its CRISPR RNA (crRNA).
C. A. Freije +12 more
semanticscholar +1 more source
Virus-derived DNA drives mosquito vector tolerance to arboviral infection
Nature Communications, 2016 Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of ...
Bertsy Goic +10 more
doaj +1 more source
Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut
iScience, 2020 Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling +9 more
doaj +1 more source
Nasopharyngeal and serological anti SARS-CoV-2 IgG/IgA responses in COVID-19 patients
Journal of Clinical Virology Plus, 2021 Background: The systemic antibody responses to SARS-CoV-2 in COVID-19 patients has been extensively studied. However, less is known about the mucosal responses in the upper airways, the site of initial SARS-CoV-2 replication.
Bernadette Crescenzo-Chaigne +10 more
doaj +1 more source