Results 271 to 280 of about 2,156,375 (387)

Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8

, 2006
Yann Hargous, Guillaume M. Hautbergue, Aura Tintaru, Lenka Skříšovská, Alexander P. Golovanov, James Stévenin, Lu Lian, Stuart A. Wilson, Frédéric H.‐T. Allain   +8 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Non-Protein-Coding RNA Instability in the Human Postmortem Brain. [PDF]

Toxicol Pathol
Dachet F, Loeb JA.
europepmc   +1 more source

Cryoelectron Microscopy Structures of Rotavirus NSP2-NSP5 and NSP2-RNA Complexes: Implications for Genome Replication

, 2006
Xiaofang Jiang, Hariharan Jayaram, Mukesh Kumar, Steven J. Ludtke, Mary K. Estes, B. V. Venkataram Prasad   +5 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

The mechanistic role of non-coding RNAs in febrile seizures in children: their potential as biomarkers and therapeutic targets-a systematic review. [PDF]

Transl Pediatr
Lian LQ, Ou WX, Ling RJ, Wang WY, Wang SY, Li SH.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

The noncoding RNA revolution—three decades and still going strong!

Molecular Oncology, 2019
George A. Calin
doaj   +1 more source

Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications. [PDF]

Endocrinol Diabetes Metab
Beniwal SS, Jeong Y, Rawat A, Einieh M, Patil K, da Costa REAR, Saini P, Ghazal KY, Kumar A, Dwivedi A, Mandavkar AA.   +10 more
europepmc   +1 more source

Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum

, 2012
Miguel Sierra-Miranda, Dulce Marı́a Delgadillo, Liliana Mâncio-Silva, Miguel Vargas, Nicolás Villegas‐Sepúlveda, Santiago Martı́nez-Calvillo, Artur Scherf, Rosaura Hernández‐Rivas   +7 more
openalex   +2 more sources