Results 281 to 290 of about 571,579 (318)
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Nanostructured RNAs for RNA Interference
2014We synthesized three types of nanostructured RNAs that induce RNA interference (RNAi): branched RNAs, dumbbell-shaped RNA, and circular double-stranded RNAs. All three nanostructured RNAs were transformed into double-stranded RNA of approximately 20 base pairs when they were treated with nuclease enzymes such as Dicer.
Yuko, Nakashima +3 more
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2014
Systematic evolution of ligands by exponential enrichment (SELEX) protocol is a valuable technique to identify RNA aptamers interacting with RNA structural motifs. RNA aptamers are mainly resolved with affinity column chromatography and electrophoretic mobility shift assay (EMSA).
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Systematic evolution of ligands by exponential enrichment (SELEX) protocol is a valuable technique to identify RNA aptamers interacting with RNA structural motifs. RNA aptamers are mainly resolved with affinity column chromatography and electrophoretic mobility shift assay (EMSA).
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RNA–RNA Interaction Prediction and Antisense RNA Target Search
Journal of Computational Biology, 2005Recent studies demonstrating the existence of special noncoding "antisense" RNAs used in post transcriptional gene regulation have received considerable attention. These RNAs are synthesized naturally to control gene expression in C. elegans, Drosophila, and other organisms; they are known to regulate plasmid copy numbers in E. coli as well. Small RNAs
Can Alkan +4 more
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Journal of Structural Biology, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Barbara L, Golden, Craig E, Kundrot
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Barbara L, Golden, Craig E, Kundrot
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RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing
Science, 2002Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA–dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing.
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Analysis RNA-seq and Noncoding RNA
2016RNA-Seq is an approach to transcriptome profiling that uses deep-sequencing technologies to detect and accurately quantify RNA molecules originating from a genome at a given moment in time. In recent years, the advent of RNA-Seq has facilitated genome-wide expression profiling, including the identification of novel and rare transcripts like noncoding ...
A. Arrigoni +6 more
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2011
Noncoding RNAs form an indispensible component of the cellular information processing networks, a role that crucially depends on the specificity of their interactions among each other as well as with DNA and protein. Patterns of intramolecular and intermolecular base pairs govern most RNA interactions.
Marz, Manja, Stadler, Peter
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Noncoding RNAs form an indispensible component of the cellular information processing networks, a role that crucially depends on the specificity of their interactions among each other as well as with DNA and protein. Patterns of intramolecular and intermolecular base pairs govern most RNA interactions.
Marz, Manja, Stadler, Peter
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Heterology among the RNAs of tymoviruses as revealed by RNA-RNA hybridizations
Virology, 1978Abstract The relationship between nucleotide sequences of the RNAs of turnip yellow mosaic virus, eggplant mosaic virus, and Andean potato latent virus was studied by using hybridization of iodinated viral RNAs with unlabeled RNase-treated nucleic acid fractions prepared from infected leaves.
J, Kummert, J P, Lacroix, J, Semal
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Trends in Genetics, 2001
The discovery of ribozymes in 1982 boosted a hypothesis in which RNA evolved and carried out biological reactions before proteins developed. Now, researchers have found a ribozyme that can replicate RNA – more evidence for this ‘RNA world’.For such a world to have existed, RNA must have catalyzed its own formation, but no known natural ribozyme can do ...
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The discovery of ribozymes in 1982 boosted a hypothesis in which RNA evolved and carried out biological reactions before proteins developed. Now, researchers have found a ribozyme that can replicate RNA – more evidence for this ‘RNA world’.For such a world to have existed, RNA must have catalyzed its own formation, but no known natural ribozyme can do ...
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RNA Remodeling by RNA Chaperones Monitored by RNA Structure Probing
2019RNA structure probing enables the characterization of RNA secondary structures by established procedures such as the enzyme- or chemical-based detection of single- or double-stranded regions. A specific type of application involves the detection of changes of RNA structures and conformations that are induced by proteins with RNA chaperone activity ...
Susann, Friedrich +2 more
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