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Biological activity of mesenchymal stem cells secretome as a basis for cell-free therapeutic approach [PDF]
Research Results in Pharmacology, 2020 Mesenchymal stem (stromal) cells (MSCs) are self-renewing, cultured adult stem cells which secrete a complex set of multiple soluble biologically active molecules such as chemokines, and cytokines, cell adhesion molecules, lipid mediators, interleukins ...
Liubov A. Pokrovskaya +4 more
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Assessment of the Immunomodulatory Properties of Human Mesenchymal Stem Cells (MSCs) [PDF]
Journal of Visualized Experiments, 2015 The immunomodulatory properties of multilineage human mesenchymal stem cells (MSCs) appear to be highly relevant for clinical use towards a wide-range of immune-related diseases. Mechanisms involved are increasingly being elucidated and in this article, we describe the basic experiment to assess MSC immunomodulation by assaying for suppression of ...
Pei-Ju, Hsu +4 more
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Cells, 2020 A multimodal therapeutic approach involving radiotherapy is required when treating head and neck squamous cell carcinoma. However, radiotherapy is restricted due to its high risk for damages to the surrounding healthy tissue of the treated area.
Mark Jakob +6 more
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Stem Cell Research & Therapy, 2021 Introduction Burned human skin, which is routinely excised and discarded, contains viable mesenchymal stromal/stem cells (burn-derived mesenchymal stromal/stem cells; BD-MSCs).
Reinhard Dolp +8 more
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Journal of Tissue Engineering, 2019 Although bone marrow–derived mesenchymal stem cells (MSCs) have been extensively explored in bone tissue engineering, only few studies using mesenchymal stem cells from mandible (M-MSCs) have been reported.
Dong Joon Lee +7 more
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Cells, 2012 Mesenchymal stem cells (MSCs) are easily accessible and safe for regenerative medicine. MSCs exert trophic, immunomodulatory, anti-apoptotic, and tissue regeneration effects in a variety of tissues and organs, but their entity remains an enigma.
Mari Dezawa +4 more
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Isolation and Characterization of Canine Wharton's Jelly-Derived Mesenchymal Stem Cells
Cell Transplantation, 2012 Wharton's jelly is a known stem cell source in humans. Because stem cells might provide a potential therapeutic role in canines, many stem cell sources are studied for isolation and characterization in the canine system.
Min-Soo Seo +2 more
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Cellular Physiology and Biochemistry, 2014 Background/Aims: Na+/H+ exchanger 1 (NHE1) is an important regulator of intracellular pH (pHi). High pHi is required for cell proliferation and differentiation.
Wei Gao +8 more
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The developmental basis of mesenchymal stem/stromal cells (MSCs) [PDF]
BMC Developmental Biology, 2015 Abstract Background Mesenchymal Stem/Stromal Cells (MSCs) define a population of progenitor cells capable of giving rises to at least three mesodermal lineages in vitro, the chondrocytes, osteoblasts and adipocytes.
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International Journal of Dentistry, 2021 Bone-marrow-derived mesenchymal stem cells (BM-MSCs) are one of the most widely studied postnatal stem cell populations and are considered to utilize more frequently in cell-based therapy and cancer.
Hamid Reza Khorasani +3 more
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