Results 11 to 20 of about 90,123 (258)
Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes. [PDF]
Stem Cells Int, 2022 Although plenty of drugs are currently available for type 2 diabetes mellitus (T2DM), a subset of patients still failed to restore normoglycemia. Recent studies proved that symptoms of T2DM patients who are unresponsive to conventional medications could be relieved with mesenchymal stem/stromal cell (MSC) therapy.
Gao S, Zhang Y, Liang K, Bi R, Du Y.
europepmc +4 more sources
Introduction to Series on Mesenchymal Stromal (Stem) Cells—MSCs [PDF]
Human Gene Therapy, 2010 Not ...
O'Brien, Timothy, Barry, Frank P.
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Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update [PDF]
Journal of Biomedical Science, 2016 Mesenchymal stem cells hold the promise to treat not only several congenital and acquired bone degenerative diseases but also to repair and regenerate morbid bone tissues. Utilizing MSCs, several lines of evidences advocate promising clinical outcomes in skeletal diseases and skeletal tissue repair/regeneration.
Saeed, Hamid +6 more
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Mesenchymal Stem Cell (MSC) Aggregate Formation in vivo [PDF]
BIO-PROTOCOL, 2014 Human mesenchymal stem/progenitor cells (MSCs) isolated from various adult tissues show remarkable therapeutic potential and are being employed in clinical trials for the treatment of numerous diseases (Prockop et al., 2010). While routes of cell administration vary, profound beneficial effects of MSCs in animal models have been observed following ...
Thomas Bartosh, Joni Ylostalo
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Indian Journal of Animal Sciences, 2021 Stem cells represent the most promising population for regenerative cell therapy and have gained much attention during the recent past. Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into trilineages. Like haematopoietic
N S RATHORE +5 more
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Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation [PDF]
Molecular Therapy, 2012 Recent observations have demonstrated that one of the functions of mesenchymal stem/stromal cells (MSCs) is to serve as guardians against excessive inflammatory responses. One mode of action of the cells is that they are activated to express the interleukin (IL)-1 receptor antagonist.
Prockop, Darwin J, Youn Oh, Joo
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Research in Pharmaceutical Sciences, 2022 Background and purpose: In vitro development of functional gametes from pluripotent stem cells is a promising prospect to treat infertility. Mesenchymal stem cells with a high degree of plasticity and less tumorigenicity are a reliable source of stem ...
Maryam Hosseinzadeh Shirzeyli +7 more
doaj +1 more source
Assessment of the Immunomodulatory Properties of Human Mesenchymal Stem Cells (MSCs) [PDF]
Journal of Visualized Experiments, 2015 The immunomodulatory properties of multilineage human mesenchymal stem cells (MSCs) appear to be highly relevant for clinical use towards a wide-range of immune-related diseases. Mechanisms involved are increasingly being elucidated and in this article, we describe the basic experiment to assess MSC immunomodulation by assaying for suppression of ...
Pei-Ju, Hsu +4 more
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Cells, 2020 A multimodal therapeutic approach involving radiotherapy is required when treating head and neck squamous cell carcinoma. However, radiotherapy is restricted due to its high risk for damages to the surrounding healthy tissue of the treated area.
Mark Jakob +6 more
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Biological activity of mesenchymal stem cells secretome as a basis for cell-free therapeutic approach [PDF]
Research Results in Pharmacology, 2020 Mesenchymal stem (stromal) cells (MSCs) are self-renewing, cultured adult stem cells which secrete a complex set of multiple soluble biologically active molecules such as chemokines, and cytokines, cell adhesion molecules, lipid mediators, interleukins ...
Liubov A. Pokrovskaya +4 more
doaj +3 more sources