Mechanotransduction in Mesenchymal Stem Cells (MSCs) Differentiation: A Review. [PDF]
Int J Mol Sci, 2022 Mechanotransduction is the process by which physical force is converted into a biochemical signal that is used in development and physiology; meanwhile, it is intended for the ability of cells to sense and respond to mechanical forces by activating intracellular signals transduction pathways and the relative phenotypic adaptation.
Raman N +4 more
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Mechanism of Action of Mesenchymal Stem Cells (MSCs): impact of delivery method. [PDF]
Expert Opin Biol Ther, 2022 Mesenchymal stromal cells (MSCs; AKA mesenchymal stem cells) stimulate healing and reduce inflammation. Promising therapeutic responses are seen in many late-phase clinical trials, but others have not satisfied their primary endpoints, making translation of MSCs into clinical practice difficult.
Bagno LL, Salerno AG, Balkan W, Hare JM.
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Mechanotransduction of mesenchymal stem cells (MSCs) during cardiomyocytes differentiation. [PDF]
Heliyon, 2022 Cardiac muscle cells have an innate capacity to perceive and react to mechanical strain via a mechanism known as mechanotransduction, whereby the cardiac muscle cells are intrinsically capable of sensing and responding to mechanical strain. This process occurs in the heart when mechanical inputs are converted to biochemical processes that result in ...
Raman N +4 more
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Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes. [PDF]
Stem Cells Int, 2022 Although plenty of drugs are currently available for type 2 diabetes mellitus (T2DM), a subset of patients still failed to restore normoglycemia. Recent studies proved that symptoms of T2DM patients who are unresponsive to conventional medications could be relieved with mesenchymal stem/stromal cell (MSC) therapy.
Gao S, Zhang Y, Liang K, Bi R, Du Y.
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Immunomodulation by Mesenchymal Stem Cells (MSCs): Mechanisms of Action of Living, Apoptotic, and Dead MSCs. [PDF]
Front Immunol, 2019 Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have been conducted with encouraging results, although the mechanisms of action behind the observed immunomodulatory capacity of mesenchymal stem cells have not been fully ...
Weiss ARR, Dahlke MH.
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The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders. [PDF]
Biomolecules, 2021 Prządka P +5 more
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Adipose-derived mesenchymal stem cells (MSCs) are a superior cell source for bone tissue engineering. [PDF]
Bioact MaterGou Y +20 more
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Isolation and Characterization of Feline Wharton’s Jelly-Derived Mesenchymal Stem Cells
Veterinary Sciences, 2021 Wharton’s jelly is a well-known mesenchymal stem cell source in many species, including humans. However, there have been no reports confirming the presence of mesenchymal stem cells in Wharton’s jelly in cats.
Min-Soo Seo +6 more
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Journal of Current Biomedical Reports, 2022 Mesenchymal stem cells (MSCs) are multipotent cells and able to differentiate into connective tissues such as bone, fat, cartilage, tendon, and muscle. They show to be very potent tools for tissue engineering and regenerative medicine. Several researches
Nooshin Barikrow, Amin Tabasi
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Introduction to Series on Mesenchymal Stromal (Stem) Cells—MSCs [PDF]
Human Gene Therapy, 2010 Not ...
O'Brien, Timothy, Barry, Frank P.
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