Results 351 to 360 of about 1,043,746 (362)

Architecture of RNA–RNA interactions

Current Opinion in Genetics & Development, 2022
RNA molecules tend to form intricate tertiary structures via intramolecular RNA-RNA interactions (RRIs) to regulate transcription, RNA processing, and translation processes. In these biological processes, RNAs, especially noncoding RNAs, usually achieve their regulatory specificity through intermolecular RNA-RNA base pairing and execute their ...
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Nanostructured RNAs for RNA Interference

2014
We synthesized three types of nanostructured RNAs that induce RNA interference (RNAi): branched RNAs, dumbbell-shaped RNA, and circular double-stranded RNAs. All three nanostructured RNAs were transformed into double-stranded RNA of approximately 20 base pairs when they were treated with nuclease enzymes such as Dicer.
Naoko Abe, Yuko Nakashima, Hiroshi Abe, Hiroshi Abe, Yoshihiro Ito   +4 more
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RNA–RNA SELEX

2014
Systematic evolution of ligands by exponential enrichment (SELEX) protocol is a valuable technique to identify RNA aptamers interacting with RNA structural motifs. RNA aptamers are mainly resolved with affinity column chromatography and electrophoretic mobility shift assay (EMSA).
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RNA–RNA Interaction Prediction and Antisense RNA Target Search

Journal of Computational Biology, 2005
Recent studies demonstrating the existence of special noncoding "antisense" RNAs used in post transcriptional gene regulation have received considerable attention. These RNAs are synthesized naturally to control gene expression in C. elegans, Drosophila, and other organisms; they are known to regulate plasmid copy numbers in E. coli as well. Small RNAs
S. Cenk Sahinalp, Can Alkan, Kaizhong Zhang, Joseph H. Nadeau, Emre Karakoc   +4 more
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RNA that synthesizes RNA

Trends in Genetics, 2001
The discovery of ribozymes in 1982 boosted a hypothesis in which RNA evolved and carried out biological reactions before proteins developed. Now, researchers have found a ribozyme that can replicate RNA – more evidence for this ‘RNA world’.For such a world to have existed, RNA must have catalyzed its own formation, but no known natural ribozyme can do ...
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RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing

Science, 2002
Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA–dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing.
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Analysis RNA-seq and Noncoding RNA

2016
RNA-Seq is an approach to transcriptome profiling that uses deep-sequencing technologies to detect and accurately quantify RNA molecules originating from a genome at a given moment in time. In recent years, the advent of RNA-Seq has facilitated genome-wide expression profiling, including the identification of novel and rare transcripts like noncoding ...
A. Arrigoni, V. Ranzani, G. Rossetti, I. Panzeri, S. Abrignani, R. J. P. Bonnal, M. Pagani   +6 more
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RNA helicases: modulators of RNA structure

Trends in Cell Biology, 1994
RNA molecules play an essential role in many cellular processes, often as components of ribonucleoprotein complexes. Like proteins, RNA molecules adopt sequence-specific secondary and tertiary structures that are essential for function; alteration of these structures therefore provides a means of regulating RNA function.
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Inhibition of RNA polymerase by RNA

Journal of Molecular Biology, 1963
Suzanne Bourgeois, François Gros, A. Tissières   +2 more
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RNA | Small RNAs in Bacteria

2021
Westra, Edze R., Jore, Matthijs M., Al-Attar, Sinan, Brouns, Stan J.J., van der Oost, John, Zaher, Hani   +5 more
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