Results 81 to 90 of about 2,156,375 (387)
Extensive translation of circular RNAs driven by N6-methyladenosine
Cell Research, 2017 Extensive pre-mRNA back-splicing generates numerous circular RNAs (circRNAs) in human transcriptome. However, the biological functions of these circRNAs remain largely unclear.
Yun Yang +12 more
semanticscholar +1 more source
Translation and functional roles of circular RNAs in human cancer
Molecular Cancer, 2020 Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed loops through backsplicing. Recent methodologies have enabled in-depth characterization of circRNAs for identification and potential functions.
Ming Lei +4 more
semanticscholar +1 more source
RNA-Catalyzed RNA Ligation on an External RNA Template [PDF]
Chemistry & Biology, 2002 Variants of the hc ligase ribozyme, which catalyzes ligation of the 3' end of an RNA substrate to the 5' end of the ribozyme, were utilized to evolve a ribozyme that catalyzes ligation reactions on an external RNA template. The evolved ribozyme catalyzes the joining of an oligonucleotide 3'-hydroxyl to the 5'-triphosphate of an RNA hairpin molecule ...
McGinness, Kathleen E, Joyce, Gerald F
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Pseudogenes, RNAs and new reproducibility norms
eLife, 2020 The partial success of a study to reproduce experiments that linked pseudogenes and cancer proves that understanding RNA networks is more complicated than expected.
George A Calin
doaj +1 more source
A quantitative comparison of sRNA-based and protein-based gene regulation [PDF]
, 2008 Small, non-coding RNAs (sRNAs) play important roles as genetic regulators in prokaryotes. sRNAs act post-transcriptionally via complementary pairing with target mRNAs to regulate protein expression.
Berg HC +5 more
core +3 more sources
Targeted oncology, 2020 Non-coding RNAs represent a significant proportion of the human genome. After having been considered as ‘junk’ for a long time, non-coding RNAs are now well established as playing important roles in maintaining cellular homeostasis and functions.
M. Ratti +6 more
semanticscholar +1 more source
RAID: a comprehensive resource for human RNA-associated (RNA–RNA/RNA–protein) interaction [PDF]
RNA, 2014 Transcriptomic analyses have revealed an unexpected complexity in the eukaryote transcriptome, which includes not only protein-coding transcripts but also an expanding catalog of noncoding RNAs (ncRNAs). Diverse coding and noncoding RNAs (ncRNAs) perform functions through interaction with each other in various cellular processes.
Zhang, Xiaomeng +23 more
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Environmental Plasticity of the RNA Content of Staphylococcus aureus Extracellular Vesicles
Frontiers in Microbiology, 2021 The roles of bacterial extracellular vesicles (EVs) in cell-to-cell signaling are progressively being unraveled. These membranous spheres released by many living cells carry various macromolecules, some of which influence host-pathogen interactions ...
Brenda Silva Rosa Da Luz +9 more
doaj +1 more source