Results 111 to 120 of about 290,253 (274)

Synthesis and evaluation of (S)-5′-C-aminopropyl and (S)-5′-C-aminopropyl-2′-arabinofluoro modified DNA oligomers for novel RNase H-dependent antisense oligonucleotides

, 2020
Yujun Zhou, Ryohei Kajino, Seiichiro Ishii, Kenji Yamagishi, Yoshihito Ueno   +4 more
openalex   +2 more sources

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex [PDF]

, 2008
Pradeep S. Pallan, Martin Egli
openalex   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis [PDF]

, 2005
Marcin Nowotny, Sergei Gaidamakov, Robert J. Crouch, Wei Yang   +3 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Direct dsRNA preparation by promoter-free RCT and RNase H cleavage using one circular dsDNA template with a mismatched bubble. [PDF]

RNA, 2023
Chen H, Gu Z, Yang L, Liu F, An R, Ge Y, Liang X.   +6 more
europepmc   +1 more source

HIV-1 Reverse Transcriptase Polymerase and RNase H (Ribonuclease H) Active Sites Work Simultaneously and Independently [PDF]

, 2016
An Li, Jiawen Li, Kenneth A. Johnson
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Expression of thermostable MMLV reverse transcriptase in Escherichia coli by directed mutation

AMB Express
The functionality of Moloney murine leukemia virus reverse transcriptase (MMLV RT) will increase with the improvement of its solubility and thermal stability.
Marzieh Divbandi, Ahad Yamchi, Hadi Razavi Nikoo, Abdolvahab Moradi, Alijan Tabarraei   +4 more
doaj   +1 more source

Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides. [PDF]

Int J Mol Sci, 2022
Kaniowski D, Kulik K, Suwara J, Ebenryter-Olbińska K, Nawrot B.   +4 more
europepmc   +1 more source