Results 161 to 170 of about 476,060 (306)
Identification of two different RNase H activities associated with yeast RNA polymerase A.
F. Iborra+4 more
openalex +1 more source
Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
CircGLIS3(2), a circRNA transiently upregulated in dermal fibroblasts during acute wound healing, is induced by IL‐1α and TGF‐β. Its RNA activates fibroblasts into matrix‐secreting cells, while its encoded protein enhances proliferation. The RNA stabilizes PCOLCE, and the protein interacts with BTF3, collectively accelerating wound repair. Abstract The
Guanglin Niu+20 more
wiley +1 more source
Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
Sequence Requirements for Removal of tRNA by an Isolated Human Immunodeficiency Virus Type 1 RNase H Domain [PDF]
Christine M. Smith+3 more
openalex +1 more source
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao+15 more
wiley +1 more source
Bounds on treewidth via excluding disjoint unions of cycles [PDF]
One of the fundamental results in graph minor theory is that for every planar graph~$H$, there is a minimum integer~$f(H)$ such that graphs with no minor isomorphic to~$H$ have treewidth at most~$f(H)$. The best known bound for an arbitrary planar $H$ is ${O(|V(H)|^9\operatorname{poly~log} |V(H)|)}$. We show that if $H$ is the disjoint union of cycles,
arxiv
Improved cloning of antibody variable regions from hybridomas by an antisense-directed RNase H digestion of the P3-X63-Ag8.653 derived pseudogene mRNA [PDF]
Christian Ostermeier
openalex +1 more source
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu+9 more
wiley +1 more source
Summary: Ribonucleases are involved in several biological processes, including the turnover of structural and messenger RNAs and the specific processing of the cellular transcriptome. Here, we characterized the RNase Y from Helicobacter pylori.
Federico D’Agostino+5 more
doaj