Results 261 to 270 of about 476,060 (306)

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He   +6 more
wiley   +1 more source

Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad

open access: green, 2007
Erkan Karakaş   +6 more
openalex   +2 more sources

Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice. [PDF]

open access: yesNucleic Acids Res, 2018
Hagedorn PH   +11 more
europepmc   +1 more source

In biomakromolekularen Komplexen können protonierte Glutamat‐ und Aspartat‐Seitenketten durch kurze und starke Wasserstoffbrückenbindungen zur Phosphodiestergruppenerkennung beitragen

open access: yesAngewandte Chemie, EarlyView.
Die stark negativ geladenen Phosphodiestergruppen von Nukleinsäuren und zyklischen (Di‐)Nukleotiden interagieren häufig mit Aminosäuren, die polare oder positiv geladene Seitenketten enthalten. Aufgrund der Ladungsabstoßung mit ihren negativ geladenen Carboxylatgruppen enthaltenden Seitenketten gelten Glutamat und Aspartat generell als ungeeignet für ...
Konstantin Neißner   +5 more
wiley   +1 more source

RNase H-assisted RNA-primed rolling circle amplification for targeted RNA sequence detection. [PDF]

open access: yesSci Rep, 2018
Takahashi H   +7 more
europepmc   +1 more source

Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate mutant of pol V<sub>ICE391</sub>. [PDF]

open access: yesDNA Repair (Amst), 2019
Walsh E   +12 more
europepmc   +1 more source

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

open access: yesAngewandte Chemie International Edition, Accepted Article.
Protein‐based tools are emerging as innovative solutions to interfere with biological pathways in molecular biology and medicine. They offer advantages over traditional small molecules due to their adaptable structural diversity and their ability to engage previously inaccessible cellular targets.
Jonathan Franke   +3 more
wiley   +1 more source

Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase. [PDF]

open access: yesJ Virol, 2018
Boyer PL   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy