Results 261 to 270 of about 476,060 (306)
RNases H: Multiple roles in maintaining genome integrity
Susana M. Cerritelli, Robert J. Crouch
openaire +3 more sources
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He+6 more
wiley +1 more source
Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice. [PDF]
Hagedorn PH+11 more
europepmc +1 more source
Die stark negativ geladenen Phosphodiestergruppen von Nukleinsäuren und zyklischen (Di‐)Nukleotiden interagieren häufig mit Aminosäuren, die polare oder positiv geladene Seitenketten enthalten. Aufgrund der Ladungsabstoßung mit ihren negativ geladenen Carboxylatgruppen enthaltenden Seitenketten gelten Glutamat und Aspartat generell als ungeeignet für ...
Konstantin Neißner+5 more
wiley +1 more source
RNase H-assisted RNA-primed rolling circle amplification for targeted RNA sequence detection. [PDF]
Takahashi H+7 more
europepmc +1 more source
Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate mutant of pol V<sub>ICE391</sub>. [PDF]
Walsh E+12 more
europepmc +1 more source
Protein‐based tools are emerging as innovative solutions to interfere with biological pathways in molecular biology and medicine. They offer advantages over traditional small molecules due to their adaptable structural diversity and their ability to engage previously inaccessible cellular targets.
Jonathan Franke+3 more
wiley +1 more source
Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase. [PDF]
Boyer PL+7 more
europepmc +1 more source