Results 261 to 270 of about 455,663 (298)
Some of the next articles are maybe not open access.
A novel protein shared by RNase MRP and RNase P
RNA (New York, N.Y.), 1997We have isolated suppressors of the temperature-sensitive rRNA processing mutation rrp2-2 in Saccharomyces cerevisiae. A class of extragenic suppressors was mapped to the YBR257w reading frame in the right arm of Chromosome II. Characterization of this gene, renamed POP4, shows that the gene product is necessary both for normal 5.8S rRNA processing and
S, Chu, J M, Zengel, L, Lindahl
openaire +2 more sources
RNase P RNA-mediated catalysis
Biochemical Society Transactions, 2002The endoribonuclease RNase P is involved in the processing of tRNA precursors to generate mature 5′ termini. The catalytic activity of RNase P is associated with an RNA, RNase P RNA. A specific interaction between the 3′ end of the substrate and RNase P RNA, to form an RNase P RNA-substrate complex, is referred to as the ‘73–294-interaction’.
openaire +2 more sources
Annual Review of Biophysics, 2013
Ribonuclease P (RNase P) is one of the first ribozymes discovered and it is found in all phylogenetic groups. It is responsible for processing the 5′ end of pre-tRNAs as well as other RNA molecules. RNase P is formed by an RNA molecule responsible for catalysis and one or more proteins.
openaire +2 more sources
Ribonuclease P (RNase P) is one of the first ribozymes discovered and it is found in all phylogenetic groups. It is responsible for processing the 5′ end of pre-tRNAs as well as other RNA molecules. RNase P is formed by an RNA molecule responsible for catalysis and one or more proteins.
openaire +2 more sources
Molecular BioSystems, 2007
Major progress in the study of RNase P has resulted from crystallography of bacterial catalytic subunits and the discovery of catalytic activity in eukaryotes. Several new substrates have also been identified, primarily in bacteria but also in yeast. Our current world should be called the "RNA-protein world" rather than the "protein world".
openaire +2 more sources
Major progress in the study of RNase P has resulted from crystallography of bacterial catalytic subunits and the discovery of catalytic activity in eukaryotes. Several new substrates have also been identified, primarily in bacteria but also in yeast. Our current world should be called the "RNA-protein world" rather than the "protein world".
openaire +2 more sources
The RNase P ofDictostyelium discoideum
Molecular Biology Reports, 1996Ribonuclease P (RNase P) is a key enzyme involved in tRNA biosynthesis. It catalyses the endonucleolytic cleavage of nearly all tRNA precursors to produce 5'-end matured tRNA. RNase P activity has been found in all organisms examined, from bacteria to mammals.
openaire +2 more sources
Characterization of RNase P RNA Activity
2012The principle task of the ubiquitous enzyme RNase P is the generation of mature tRNA 5'-ends by removing precursor sequences from tRNA primary transcripts (Trends Genet 19:561-569, 2003; Crit Rev Biochem Mol Biol 41:77-102, 2006; Trends Biochem Sci 31:333-341, 2006).
Markus, Gössringer +2 more
openaire +2 more sources
RNase P in Research and Therapy
Nature Biotechnology, 1995Fooling the catalytic RNA subunit into recognizing nonnatural substrates may have important implications for ...
openaire +2 more sources
Further characterization of human RNase MRP/RNase P and related autoantibodies
Molecular Biology Reports, 1998We characterized a panel of human RNase MRP/RNase P autoantibodies by immunoprecipitation, immunodepletion, immunoaffinity purification and immunoblotting. We report on the protein spectrum that is recognized by RNase MRP/RNase P autoantibodies. We also describe another, related patient serum that based on these assays does not immunoprecipitate RNase ...
openaire +2 more sources
Yeast mitochondrial RNase P: an unusual member of the RNase P enzyme family
1995We review here our studies of the tRNA processing enzyme, RNase P. Yeast mitochondrial RNase P contains an AU-rich mitochondrial coded RNA which varies in size in different yeasts. All of these RNAs contain two short sequences with similarity to two sequences found in all RNase P RNAs.
G.-J. Gao +3 more
openaire +1 more source
2009
RNase P is an almost universal enzyme present in Bacteria, Archaea and Eukaryotic nuclei, as well as in mitochondria and chloroplasts. The organellar enzyme shows a great variability in structure and composition. A gene encoding an RNA, homologous to bacterial catalytic RNase P RNA, is found in mitochondria of a diversity of organisms that include ...
openaire +1 more source
RNase P is an almost universal enzyme present in Bacteria, Archaea and Eukaryotic nuclei, as well as in mitochondria and chloroplasts. The organellar enzyme shows a great variability in structure and composition. A gene encoding an RNA, homologous to bacterial catalytic RNase P RNA, is found in mitochondria of a diversity of organisms that include ...
openaire +1 more source