Results 231 to 240 of about 299,739 (289)

The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution. [PDF]

Open Biol
Pan JM, Betts H, Cubbon A, He L, Bolt EL, Soultanas P.   +5 more
europepmc   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Protocol for direct cDNA cap analysis of gene expression for paired-end patterned flow cell sequencing. [PDF]

STAR Protoc
Delobel D, Nishiyori-Sueki H, Nisoli I, Kawaji H, Robbe P, Carninci P, Takahashi H.   +6 more
europepmc   +1 more source

Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges

Advanced Genetics, EarlyView.
This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley   +1 more source

O-GlcNAcylation reduces proteome solubility and regulates the formation of biomolecular condensates in human cells. [PDF]

Nat Commun
Xu S, Yin K, Xu X, Fu L, Wu R.
europepmc   +1 more source

Investigation of endoplasmic reticulum stress parameters in patients with gestational diabetes mellitus: A prospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Our aim in this study was to evaluate the levels of Activating Transcription Factor‐6 (ATF‐6), Inositol‐Requiring Enzyme 1 (IRE‐1), and C/EBP‐Homologous Protein (CHOP), which are critical markers of endoplasmic reticulum (ER) stress, in patients with gestational diabetes mellitus (GDM), a condition increasingly recognized for its ...
Sevcan Sarıkaya, Eissa Almaghrebi, Fatma Akat, Eda Nur Hepbildi, Esra Kosucu, Muslu Kazım Körez, Husamettin Vatansev   +6 more
wiley   +1 more source

An RNA ligase partner for the prokaryotic protein-only RNase P: insights into the functional diversity of RNase P from genome mining. [PDF]

mBio
Seshadri R, Gopalan V.
europepmc   +1 more source

Rapid and Visual Detection of Mycobacterium tuberculosis Complex Based on Multiplex Recombinase Polymerase Amplification

iLABMED, EarlyView.
We developed an on‐site detection platform for rapid detection of Mycobacterium tuberculosis complex (MTBC) based on the IS1081 gene. The platform utilizes real‐time multiplex recombinase polymerase amplification (mRPA) to achieve a reaction time of less than 30 min.
Xiaoyan Tan, Yongcong Li, Xufu Xiang, Wei Wu, Gang Wang, Sai Zhang   +5 more
wiley   +1 more source

Nano-delivery platform with strong protection and efficient delivery: preparation of self-assembled RNA pesticide with dual RNAi targets against Apolygus lucorum. [PDF]

J Nanobiotechnology
Qiao H, Jiang Q, Zhao J, Xiao L, Zhu-Salzman K, Xu D, Xu G, Shen J, Gu A, Hao D, Yan S, Tan Y.   +11 more
europepmc   +1 more source

Biotechnological Potential of the Fusarium fujikuroi Complex From Amazonian Oenocarpus bacaba: Lipase Production and Characterization

Journal of Basic Microbiology, EarlyView.
ABSTRACT This study investigates the diversity of filamentous fungi in the Amazon biome, particularly the genus Fusarium, known for producing biotechnologically valuable metabolites. The research aimed to isolate and identify fungi from Oenocarpus bacaba Mart.
Lucely Nogueira dos Santos, Rafael Firmani Perna, Ana Carolina Vieira, Kalebe Ferreira Furtado, Alex Fernando de Almeida, Cristiane Angélica Ottoni, Leandro Mantovani de Castro, Felipe Mello, Yoannis Domínguez, Nelson Rosa Ferreira   +9 more
wiley   +1 more source