Results 51 to 60 of about 23,184 (200)

Percurso do doente – Doença de Huntington / Patient journey – Huntington's disease

open access: yes, 2023
<p><strong>ENG</strong></p><p>Patient Journeys  are info-graphical overviews that visualize patients' needs in the care of their rare disease.
Alves Ferreira, João Miguel
core   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar   +7 more
wiley   +1 more source

Relaxation rate of RNdS black hole

open access: yesPhysics Letters B, 2020
8 pages, to appear in ...
Ming Zhang, Jie Jiang, Zhen Zhong
openaire   +4 more sources

Percurso do doente – Paraplegia Espastica Hereditaria (PEH) / Patient Journey Hereditary Spastic Paraplegias (HSPs)

open access: yes, 2023
<p><strong>ENG</strong></p><p>Patient Journeys  are info-graphical overviews that visualize patients' needs in the care of their rare disease.
Alves Ferreira, João Miguel
core   +1 more source

Energy coupling mechanisms of AcrB-like RND transporters [PDF]

open access: yesBiophysics Reports, 2017
Prokaryotic AcrB-like proteins belong to a family of transporters of the RND superfamily, and as main contributing factor to multidrug resistance pose a tremendous threat to future human health. A unique feature of AcrB transporters is the presence of two separate domains responsible for carrying substrate and generating energy.
Zhang, Xuejun C., Liu, Min, Han, Lei
openaire   +2 more sources

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

open access: yesAdvanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song   +9 more
wiley   +1 more source

Innovation Pathways to Carbon Efficiency: Disentangling the Effects of AI, R&D, and Clean Energy Blessings on U.S. Environmental Sustainability

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The United States (U.S.) faces challenges in achieving its ambitious net‐zero carbon emissions target by 2050, with current emissions having fallen by less than 1% in 2024. Despite an investment of $500 billion in low‐carbon resources while holding the second‐largest green technology patent portfolio globally, it is further imperative to ...
Md Zubair Ahmad   +5 more
wiley   +1 more source

„Der Geist ist aus der Flasche“ : Vogelgrippevirus H5N1: Wie konnte der Erreger so gefährlich werden?

open access: yes, 2023
Innerhalb kurzer Zeit haben sich Vogelgrippeviren wie H5N1 weltweit verbreitet. Das Problem ist nicht nur, dass sie leicht übertragbar sind, sondern dass sie auch auf Tiere treffen, die noch nie mit solchen Erregern Kontakt hatten.
RND/dpa
core  

Beyond Linear ESG Effects: Configurational Pathways to Superior Profitability Among Environmental Proactive Firms

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study re‐examines the relationship between environmental, social, and governance (ESG) engagement and firm financial performance by moving beyond linear, net‐effect models toward a configurational perspective. Focusing on a global sample of 1380 non‐financial firms with high environmental maturity (CDP Climate Change score ≥ B), we ...
Daniel Yeung   +2 more
wiley   +1 more source

Repairing the Microsoft BASIC RND function [PDF]

open access: yesBehavior Research Methods, Instruments, & Computers, 1988
Difficulties with the Microsoft BASIC function for generating random numbers (RND) are cited and new problems reported. Fixes are suggested that allow use of some of the speed of the original function and that produce greatly improved pseudorandom numbers. A published generator is combined with the RND function as a compromise solution.
openaire   +1 more source

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