Results 31 to 40 of about 13,181 (183)

RND multidrug efflux pumps: what are they good for? [PDF]

open access: yesFrontiers in Microbiology, 2013
Multidrug efflux pumps are chromosomally encoded genetic elements capable of mediating resistance to toxic compounds in several life forms. In bacteria, these elements are involved in intrinsic and acquired resistance to antibiotics. Unlike other well-known horizontally acquired antibiotic resistance determinants, genes encoding for multidrug efflux ...
Alvarez-Ortega, Carolina   +2 more
openaire   +4 more sources

A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB

open access: yesScientific Reports, 2022
Tripartite resistance-nodulation-division (RND) efflux pumps, such as AcrAB-TolC of Salmonella Typhimurium, contribute to antibiotic resistance and comprise an inner membrane RND-transporter, an outer membrane factor, and a periplasmic adaptor protein ...
Ilyas Alav   +2 more
doaj   +1 more source

Pseudomonas cannabina pv. alisalensis Virulence Factors Are Involved in Resistance to Plant-Derived Antimicrobials during Infection

open access: yesPlants, 2022
Bacteria are exposed to and tolerate diverse and potentially toxic compounds in the natural environment. While efflux transporters are generally thought to involve bacterial antibiotic resistance in vitro, their contributions to plant bacterial virulence
Nanami Sakata   +4 more
doaj   +1 more source

The ins and outs of RND efflux pumps in Escherichia coli [PDF]

open access: yesFrontiers in Microbiology, 2015
Infectious diseases remain one of the principal causes of morbidity and mortality in the world. Relevant authorities including the WHO and CDC have expressed serious concern regarding the continued increase in the development of multidrug resistance among bacteria.
Anes   +4 more
openaire   +3 more sources

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance

open access: yesBMC Microbiology, 2009
Background Burkholderia cenocepacia are opportunistic Gram-negative bacteria that can cause chronic pulmonary infections in patients with cystic fibrosis.
Venturi Vittorio   +8 more
doaj   +1 more source

Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

open access: yesMicrobiology Spectrum, 2022
Bacterial efflux pumps in the resistance-nodulation-cell division (RND) family of Gram-negative bacteria contribute significantly to the development of antimicrobial resistance by many pathogens. In this study, we selected the MtrD transporter protein of
Meinan Lyu   +5 more
doaj   +1 more source

GAMBARAN KARAKTERISTIK SAFETY LEADERSHIP PT. RND DI JAKARTA-SURABAYA TAHUN 2012

open access: yesBioLink, 2017
This reseach will describe and explain the overall the characteristics of safety leadership in PT. RND, Jakarta-Surabaya in 2012 with in-depth interviews and direct observation for the leaders in PT. RND conducted in April-June 2012.
Desyawati Utami
doaj   +1 more source

Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins. [PDF]

open access: yesPLoS ONE, 2017
The Rnd family of proteins, Rnd1, Rnd2 and Rnd3, are atypical Rho family GTPases, which bind to but do not hydrolyse GTP. They interact with plexins, which are receptors for semaphorins, and are hypothesised to regulate plexin signalling.
Thomas Wylie   +3 more
doaj   +1 more source

Evolution of RND efflux pumps in the development of a successful pathogen

open access: yesDrug Resistance Updates, 2023
This study examined the origins and evolution of the AdeABC, AdeFGH and AdeIJK efflux pumps in the Acinetobacter genus, including human and animal pathogens and species from non-clinical environments.Comparative genome analyses were performed using the reference sequences for 70 Acinetobacter species to identify putative orthologs of AdeABC, AdeFGH and
Naidu, Varsha   +7 more
openaire   +3 more sources

Relaxation rate of RNdS black hole

open access: yesPhysics Letters B, 2020
8 pages, to appear in ...
Ming Zhang, Jie Jiang, Zhen Zhong
openaire   +4 more sources

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