Results 21 to 30 of about 13,181 (183)

Vibrio cholerae VexH encodes a multiple drug efflux pump that contributes to the production of cholera toxin and the toxin co-regulated pilus. [PDF]

PLoS ONE, 2012
The resistance-nodulation-division (RND) efflux systems are ubiquitous transporters that function in antimicrobial resistance. Recent studies showed that RND systems were required for virulence factor production in Vibrio cholerae. The V. cholerae genome
Dawn L Taylor, Xiaowen R Bina, James E Bina   +2 more
doaj   +1 more source

On the RND under Heston's Stochastic Volatility Model [PDF]

SSRN Electronic Journal, 2021
We consider Heston's (1993) stochastic volatility model for valuation of European options to which (semi) closed form solutions are available and are given in terms of characteristic functions. We prove that the class of scale-parameter distributions with mean being the forward spot price satisfies Heston's solution.
openaire   +3 more sources

Effect of a Recliner Chair with Rocking Motions on Sleep Efficiency

Sensors, 2021
In this study, we analyze the effect of a recliner chair with rocking motions on sleep quality of naps using automated sleep scoring and spindle detection models.
Suwhan Baek, Hyunsoo Yu, Jongryun Roh, Jungnyun Lee, Illsoo Sohn, Sayup Kim, Cheolsoo Park   +6 more
doaj   +1 more source

Tripartite assembly of RND multidrug efflux pumps [PDF]

Nature Communications, 2016
Abstract Tripartite multidrug efflux systems of Gram-negative bacteria are composed of an inner membrane transporter, an outer membrane channel and a periplasmic adaptor protein. They are assumed to form ducts inside the periplasm facilitating drug exit across the outer membrane. Here we present the reconstitution
Daury, Laetitia; Orange, Francois; Taveau, Jean-Christophe; Verchere, Alice; Monlezun, Laura; Gounou, Celine; Marreddy, Ravi K. R.; Picard, Martin; Broutin, Isabelle; Pos, Klaas M.; Lambert, Olivier   +11 more
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The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors [PDF]

Journal of Biological Chemistry, 2012
Rnd proteins are Rho family GTP-binding proteins with cellular functions that antagonize RhoA signaling. We recently described a new Rnd3 effector Syx, also named PLEKHG5, that interacts with Rnds via a Raf1-like "Ras-binding domain." Syx is a multidomain RhoGEF that participates in early zebrafish development. Here we demonstrated that Rnd1, Rnd2, and
Liuh Ling, Goh, Ed, Manser
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RND transporters in the living world [PDF]

Research in Microbiology, 2018
Transporters of the RND superfamily are well-known as the major drug efflux pumps of Gram-negative bacteria. However, they are widespread in organisms ranging from Archaea to Eukaryotes, and perform diverse functions. This review gives a brief overview of these diverse members of the superfamily with emphasis on their structure and functions.
openaire   +4 more sources

Structural basis of RND-type multidrug exporters [PDF]

Frontiers in Microbiology, 2015
Bacterial multidrug exporters are intrinsic membrane transporters that act as cellular self-defense mechanism. The most notable characteristics of multidrug exporters is that they export a wide range of drugs and toxic compounds. The overexpression of these exporters causes multidrug resistance.
Yamaguchi, Akihito, Nakashima, Ryosuke, Sakurai, Keisuke   +2 more
openaire   +3 more sources

The Experience of a Tertiary Reference Hospital in the Study of Rare Neurological Diseases

Medicina, 2023
Background and Objectives: Rare diseases (RDs) are life-threatening or chronically impairing conditions that affect about 6% of the world’s population. RDs are often called ‘orphan’ diseases, since people suffering from them attract little support from ...
Styliani-Aggeliki Sintila, Marina Boziki, Christos Bakirtzis, Thomai Stardeli, Nikoletta Smyrni, Ioannis Nikolaidis, Dimitrios Parissis, Theodora Afrantou, Theodore Karapanayiotides, Ioanna Koutroulou, Virginia Giantzi, Paschalis Theotokis, Evangelia Kesidou, Georgia Xiromerisiou, Efthimios Dardiotis, Panagiotis Ioannidis, Nikolaos Grigoriadis   +16 more
doaj   +1 more source

Variantes del algoritmo CHC para proyectar redes de radio frecuencia en comunicaciones inalámbricas

Informes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral), 2015
En el presente trabajo se aplica una serie de versiones del algoritmo genético no convencional denominado Cross generational elitist selection Heterogeneous recombination Cataclysmic mutation algorithm (CHC ) para resolver el problema de diseño de red de
Daniel Antonio Molina, Daniel Raul Pandolfi, Norma Andrea Villagra, Guillermo Leguizamón   +3 more
doaj   +1 more source

An RND transporter in the monoterpene metabolism of Castellaniella defragrans [PDF]

Biodegradation, 2018
The betaproteobacterium Castellaniella defragrans 65Phen grows on monoterpenes at concentrations toxic to many bacteria. Tolerance mechanisms include modifications of the membrane fatty acid composition and the mineralization of monoterpenes. In this study, we characterized an efflux transporter associated to the monoterpene metabolism.
Edinson Puentes-Cala, Jens Harder
openaire   +3 more sources