Results 141 to 150 of about 66,164 (300)

Defect‐engineered tungsten oxide nanowires as redox‐metabolic nanozymes for gut inflammation‐infection syndromes

open access: yesBMEMat, EarlyView.
Defect‐engineered WO3 nanowires serve as a multifunctional nanozyme platform to treat IBD complicated by Salmonella co‐infection. By integrating catalytic ROS/RNS scavenging and targeted metabolic interference of pathogens via molybdenum substitution, these nanowires effectively resolve intestinal oxidative stress, inhibit infection, and restore ...
Yifan Yuan   +13 more
wiley   +1 more source

RECEPTORES NUCLEARES: DEL NÚCLEO AL CITOPLASMA

open access: yesTIP Revista Especializada en Ciencias Químico-Biológicas, 2015
Los receptores nucleares (RNs) constituyen una familia de factores transcripcionales activados por ligando que regulan la expresión de un gran número de genes de forma dependiente del tipo y contexto celular.
Bibiana Ortega-Domínguez   +2 more
doaj  

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino   +7 more
wiley   +1 more source

Virtual Reality in Medical Education: A Concept Analysis

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Virtual reality (VR) remains inconsistently defined in medical education, with the term being applied to heterogeneous immersive and nonimmersive technologies. This inconsistency may hinder intervention classification, evidence synthesis, curriculum planning, and technology selection.
Arthur Rodrigues Lima   +7 more
wiley   +1 more source

Chiral‐at‐Metal Racemization of Tris‐Chelated Octahedral Complexes: A DFT Case Study of Al(acnac)3

open access: yesChemistry – A European Journal, EarlyView.
Racemization and isomerization of M(a‐chel)3 complexes was unraveled using Al(acnac)3 as a model. The ∆/Λ‐fac isomers have four racemization paths of which one includes isomerization to and racemization of the mer isomer. N‐substitution should enable separation of the ∆‐fac and Λ‐fac enantiomers.
George Dhimba   +2 more
wiley   +1 more source

Analysis of the Regulatory Framework for the CCU Technology

open access: yesChemie Ingenieur Technik, EarlyView.
ABSTRACT Carbon capture and utilisation (CCU) is increasingly considered an important technology for achieving climate neutrality within the German and European legal framework. Recent developments, particularly the Carbon Dioxide Storage and Transport Act (KSpTG), aim to enable CO2 transport infrastructure and cross‐sector carbon management systems ...
Sophie Schmengler   +2 more
wiley   +1 more source

Copula‐based joint modelling of emergency department visits with time‐varying dependence

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Jointly modelling multiple correlated count time series is essential in health services research, where outcomes like emergency visits for mental health and substance use often evolve together. Ignoring these dependencies can obscure meaningful trends and limit the effectiveness of policy evaluation.
Guanjie Lyu, Cindy Feng, Lihui Liu
wiley   +1 more source

CYP2D6‐Guided Opioid Therapy for Chronic Pain: A Multi‐Center Pragmatic Randomized Controlled Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The analgesic effectiveness of several opioids depends on CYP2D6‐mediated metabolism to more active opioid receptor agonists. CYP2D6 activity is impacted by genetic variability and medications that inhibit CYP2D6. We conducted a pragmatic, multi‐center, randomized, controlled trial to determine whether CYP2D6‐guided opioid prescribing improves chronic ...
Todd C. Skaar   +255 more
wiley   +1 more source

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