Results 161 to 170 of about 66,164 (300)

Oxidative Stress in Animals: A Systematic Analysis from Signaling Pathways to Biological Effects. [PDF]

Life (Basel)
Chang L, Liu C, Huang G.
europepmc   +1 more source

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner, Faith C. Robertson, Nathaniel D. Sisterson, Gabriel Lazaro‐Munoz, Florence T. Bourgeois, James W. Wheless, Steven M. Wolf, Peter C. Warnke, Saadi Ghatan, Joffre Olaya, Catherine J. Chu, Brian N. Lundstrom, Sanjeev V. Kothare, Marytery Fajardo, Marike L. D. Broekman, R. Mark Richardson   +15 more
wiley   +1 more source

Reply to Doyle: Emphasizing independent gene duplications and convergent molecular function. [PDF]

Proc Natl Acad Sci U S A
Finegan C, Kates HR, Guralnick RP, Soltis PS, Resende MFR, Ané JM, Kirst M, Folk RA, Soltis DE.   +8 more
europepmc   +1 more source

Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie, Arianna Damiani, Mahsa Khoshkhou, Luis A. Sanchez, Rachel J. Smith, Shruti H. Agashe, Jorge A. Gonzalez‐Martinez, Jennifer Hopp, Adam S. Charles, Sridevi V. Sarma, Joon‐Yi Kang   +10 more
wiley   +1 more source

Biomimetic hierarchical heterogeneity endows layered nanocomposite with excellent mechanical and electrical insulating properties. [PDF]

Sci Adv
Yu GH, Pan XF, Xu WL, Zhu YB, Chen SM, Yu SH.   +5 more
europepmc   +1 more source

Seizure forecasting: The long and winding road to clinical translation

Epilepsia, EarlyView.
Abstract Seizure forecasting has progressed from theoretical aspiration to a rapidly advancing research domain, yet clinical translation remains limited. Over the past decades, advances in algorithm development, chronic electroencephalography (EEG), wearable sensors, and the characterization of seizure cycles have demonstrated that seizure risk is not ...
Philippa J. Karoly, Rachel E. Stirling, Mark J. Cook, Daniel M. Goldenholz, Maxime O. Baud, Vikram R. Rao, Solveig Vieluf, Benjamin H. Brinkmann   +7 more
wiley   +1 more source

Acute Sleep Deprivation Is Associated with Altered F-Wave Temporal Dynamics and Nasalis Repetitive Nerve Stimulation Responses: A Paired Electrophysiological Study. [PDF]

Brain Sci
İnalkaç Gemici Y, Sönmez EC.
europepmc   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

Epilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Nissolia brasiliensis as a nonnodulating model legume. [PDF]

Plant Physiol
Girou C, Keller J, Libourel C, van Beveren F, Bianconi M, Dufau I, Cravero C, Callot C, Rodde N, Cauet S, Coriton O, Huteau V, Delaux PM, Vernié T.   +13 more
europepmc   +1 more source

Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms

Epilepsia, EarlyView.
Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong, Ewan S. Nurse, Ashley Reynolds, Mark J. Cook, Philippa J. Karoly   +4 more
wiley   +1 more source